USES
The Auvi-Q is meant to be simple to use, even for a frantic or emergency situation. The device has voice instructions to lead the user through each step. Here’s how to use the device:
Take the Auvi-Q from its case and hold it firmly in your hand.
Push off the safety cap on the device. The device will then automatically be ready for use.
Put the black end (needle end) firmly against outer thigh. It can be given through clothing if needed.
Press down firmly to activate the device. You should hear a click, which means injection is going to happen.
Keep the device in place for 5 seconds to assure delivery of the full dose
Take the device away and massage the injection site for a few seconds.
WORKING
Auvi-Q works by administering epinephrine, a synthetic version of adrenaline. Epinephrine is a hormone produced by the adrenal glands; it helps to counteract the effects of anaphylaxis through the following actions:
It causes contraction of blood vessels, thereby raising the blood pressure that anaphylaxis has lowered.
It relaxes the airway muscles to make breathing easier for the person who suffers from anaphylaxis.
It reduces swelling in the throat and face, which can be life-threatening in an allergic reaction .
Increases the heart rate to ensure proper circulation and oxygenation of the body.
SIDE EFFECTS
While Auvi-Q can be life-saving, still there are some possible side effects of epinephrine injection:
Common Side Effects:
Shaky hands or anxiety
Headache
Dizziness
Paleness
Severe Side Effects (although rare but may occur):
Severe allergic reactions to epinephrine itself (with rash, itching, or swelling)
Hypertension or high blood pressure
Stroke or heart attack in those with certain heart conditions
Severe shortness of breath or chest pain
Severe anxiety or nervousness
WARNINGS
Heart Conditions: Individuals with certain heart conditions, such as high blood pressure, coronary artery disease, or a history of stroke, should use Auvi-Q with caution, as epinephrine can increase heart rate and blood pressure, potentially causing complications.
Pregnancy and Breastfeeding: Use of Auvi-Q during pregnancy or breastfeeding requires discussion with a healthcare provider. Epinephrine should be prescribed only after the potential benefits apparently outweigh potential risks. Use in pregnancy only if clearly needed.
Multiple Injections: If symptoms of anaphylaxis continue or recur following the initial injection, a second dose might be administered. A second device should be available, and the patient should remain under medical attention even if their symptoms seem to abate following administration of the first dose.
INTERACTIONS
Beta-Blockers: Taking beta-blockers (e.g., propranolol, metoprolol) with Auvi-Q may reduce the effectiveness of epinephrine in treating anaphylaxis, as beta-blockers can inhibit the action of epinephrine on the heart and blood vessels.
Monoamine Oxidase Inhibitors (MAOIs): Using Auvi-Q with MAOIs (e.g., phenelzine, tranylcypromine) may increase the risk of high blood pressure and other cardiovascular side effects due to the potential for enhanced adrenergic effects of epinephrine.
Tricyclic Antidepressants (TCAs): Combining Auvi-Q with tricyclic antidepressants (e.g., amitriptyline) can increase the risk of elevated blood pressure and heart rate, as these medications may have additive effects with epinephrine.
Other Sympathomimetics: Using other sympathomimetic drugs (e.g., pseudoephedrine, certain asthma medications) alongside Auvi-Q may increase the risk of cardiovascular side effects like increased heart rate, hypertension, and arrhythmias.
DOSAGE
The dosage of Auvi-Q is based on the patient’s body weight as follows:
0.1 mg (0.1 mL) dose : for children weighing 16.5 to 33 pounds.
0.15 mg (0.3 mL) dose: Infants weighing 33 to 66 pounds.
0.3 mg (0.3 mL) dose: Patients weighing more than 66 pounds or for adults.
If an individual received a dose, the patient should be observed for the relapse of anaphylaxis and second doses should be provided once symptoms persist after 5-15 minutes.
PRESCRIPTION
Auvi-Q is a prescription-only medication. A healthcare provider will prescribe it according to the individual needs that can necessitate their doctor-prescribed for an individual. This could be risk such as the patient having an anaphylaxis due to allergies.
Once prescribed, a person with known severe allergies should carry an Auvi-Q everywhere and it is recommended to have another in place such as in home, work, or school.
FAQ's
What is Auvi-Q?
Auvi-Q is an epinephrine auto-injector used to treat severe allergic reactions, including anaphylaxis.
How does Auvi-Q work?
It contains epinephrine, which constricts blood vessels, relaxes airway muscles, and reverses hives while increasing heart rate during an allergic reaction.
Who should use Auvi-Q?
Auvi-Q is prescribed for individuals at risk of anaphylaxis due to allergies to foods, insect stings, medications, or other allergens.
What do I do if I experience an allergic reaction?
If you have a severe allergic reaction, use Auvi-Q as directed and seek emergency medical assistance immediately.
How do I store Auvi-Q?
Store Auvi-Q at room temperature, away from light and moisture. Do not refrigerate or freeze it.
What are the side effects of using Auvi-Q?
Common side effects include increased heart rate, dizziness, headache, and anxiety. Severe side effects are rare but can occur.
Is Auvi-Q suitable for children?
Yes, Auvi-Q can be prescribed for children, but the dosage depends on the child’s weight and age.
How can I tell if my Auvi-Q is expired?
Check the expiration date printed on the label. Do not use Auvi-Q after this date.
What should I do if my Auvi-Q is damaged?
If your Auvi-Q is cracked, leaking, or damaged, replace it and notify your pharmacy.
Can I use Auvi-Q if I am pregnant or breastfeeding?
Consult your healthcare provider to determine if Auvi-Q is safe for you during pregnancy or while breastfeeding.
How do I use Auvi-Q in an emergency?
Pull off the safety cap, press the injector firmly against the outer thigh, and hold for 5 seconds while the medication is delivered.
Can I take Auvi-Q with other medications?
Always inform your doctor about all medications you are taking, as some may interact with epinephrine.
What should I do after administering Auvi-Q?
After using Auvi-Q, call for emergency medical help immediately, as further treatment may be necessary.
Is it normal to feel anxious after using Auvi-Q?
Yes, anxiety can be a common side effect due to the adrenaline released from epinephrine.
Does Auvi-Q require a prescription?
Yes, Auvi-Q requires a prescription from a healthcare provider.
Can I use Auvi-Q more than once during an allergic reaction?
If symptoms do not improve after 5 to 15 minutes, or worsen, a second dose may be administered. Always consult a doctor.
What should I carry with me when I have Auvi-Q?
Always carry your Auvi-Q and have an emergency plan in place with friends and family.
Where can I get a replacement for a lost Auvi-Q?
You can get a prescription refill from your healthcare provider or pharmacy.
Are there any age restrictions for using Auvi-Q?
There are no strict age restrictions, but it should be used under adult supervision for children.
Can I find Auvi-Q at any pharmacy?
Auvi-Q is available at most pharmacies, but it’s best to call ahead to check availability.