Chloroxylenol, hydrocortisone, and pramoxine (otic)

Common Brands Cortisporin Otic Solution (similar combination), generic combos
Drug Class
Antiseptic, corticosteroid, local anesthetic (otic use)
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Prescription only
Kristianne Hannemann, PharmD
Kristianne Hannemann, PharmD
★★★★★
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Medically reviewed by Kristianne Hannemann, PharmD last update on 20/12/2023

Overview

Chloroxylenol, Hydrocortisone, and Pramoxine are a combination of three active ingredients used in otic preparations, which are applied directly into the ear to treat ear infections and related symptoms. These medications are typically formulated to relieve discomfort, reduce inflammation, and fight infection within the ear canal. This combination is commonly used for conditions such as swimmer’s ear (otitis externa), ear canal inflammation, and ear itching.

Each ingredient plays a distinct role in the treatment:

  • Chloroxylenol acts as an antiseptic to prevent bacterial growth and infection in the ear canal.
  • Hydrocortisone is a corticosteroid that reduces inflammation, redness, and swelling in the ear.
  • Pramoxine is a local anesthetic that helps relieve itching and pain by numbing the affected area.

Together, these components work to provide relief from pain, itching, and inflammation, while also treating underlying infection.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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