Abacavir

Common Brands Actos
Drug Class
Thiazolidinedione
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Prescription only
Robert Chad Hakim, PharmD, BCCCP
Robert Chad Hakim, PharmD, BCCCP
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Medically reviewed by Robert Chad Hakim, PharmD, BCCCP last update on 20/12/2023

Overview

Abacavir, commonly known by its brand name Ziagen, is a potent antiretroviral medication primarily used in the management of Human Immunodeficiency Virus (HIV) infection. This nucleoside reverse transcriptase inhibitor (NRTI) is a crucial component of combination therapies aimed at suppressing the replication of the virus, thereby slowing the progression of HIV/AIDS.

Abacavir interferes with the reverse transcriptase enzyme, a key component in the replication cycle of the HIV virus. By inhibiting this enzyme, Abacavir prevents the conversion of viral RNA into DNA, ultimately hindering the virus’s ability to integrate into the host cell’s genetic material.

Abacavir is available in various forms, including tablets and oral solutions, allowing for flexibility in dosing. The diverse presentations cater to different patient populations, ensuring accessibility and ease of administration.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy