Acrivastine is a versatile antihistamine widely prescribed to address various allergic conditions. Its primary uses revolve around providing effective relief from symptoms associated with allergic rhinitis and urticaria.

Allergic Rhinitis (Hay Fever)

Acrivastine is commonly employed to alleviate the symptoms of allergic rhinitis, a condition triggered by exposure to allergens like pollen, pet dander, or dust mites. Symptoms include sneezing, nasal congestion, itching, and a runny nose. Acrivastine’s targeted action on histamine receptors helps mitigate these symptoms, providing rapid and effective relief.

Urticaria (Hives)

Acrivastine is also utilized in the treatment of urticaria, a skin condition characterized by the sudden appearance of itchy welts or hives. These welts can vary in size and shape and often appear as an allergic reaction to certain foods, medications, or environmental factors. Acrivastine helps alleviate the itching and discomfort associated with hives, providing relief to individuals experiencing this allergic skin reaction.

Seasonal and Perennial Allergies

Whether triggered by seasonal factors like pollen during spring or persistent allergens like pet dander year-round, Acrivastine is effective in managing both seasonal and perennial allergic reactions. Its rapid onset of action makes it a valuable option for individuals seeking quick relief from allergy symptoms.

Itching and Watery Eyes

Acrivastine’s antihistamine properties extend to addressing itching and watery eyes, common symptoms experienced during allergic reactions. By blocking histamine release, Acrivastine helps reduce ocular symptoms, contributing to an overall improvement in the quality of life for individuals dealing with allergies.

How it works

Acrivastine functions by selectively inhibiting the H1 histamine receptor. By blocking the action of histamine, it prevents the typical allergy symptoms. Unlike some older antihistamines, Acrivastine has a lower likelihood of causing sedation due to its limited penetration into the central nervous system.

Acrivastine, like any medication, may have side effects, though they are generally well-tolerated. It’s crucial to be aware of potential reactions, both common and serious, while using Acrivastine.

Common Side Effects

• Dry Mouth: A commonly reported side effect, individuals taking Acrivastine may experience a sensation of dryness in the mouth. 
• Headache: Some users may experience mild headaches as a side effect of Acrivastine. Ensuring proper hydration and, if needed, consulting a healthcare professional for headache management is recommended.
• Fatigue: While Acrivastine is a second-generation antihistamine known for its reduced sedative effects, some individuals may still experience mild fatigue. It is advisable to avoid activities that require mental alertness until the individual’s response to the medication is known.

While Acrivastine is generally well-tolerated, it’s essential to be aware of certain precautions and warnings to ensure safe and effective use:

Allergic Reactions

Individuals with a history of allergic reactions to antihistamines or any components of Acrivastine should exercise caution and consult a healthcare professional before use.

Drowsiness

Acrivastine may cause drowsiness in some individuals. Caution is advised, especially when operating heavy machinery or driving, until the individual’s response to the medication is known.

Pregnancy and Breastfeeding

Pregnant or breastfeeding women should consult with their healthcare provider before using Acrivastine to assess potential risks and benefits.

Renal Impairment

Individuals with renal impairment may require dosage adjustments. It’s crucial to consult a healthcare professional for personalized guidance in such cases.

Other Medications

Acrivastine may interact with certain medications, including erythromycin and ketoconazole.

Acrivastine has the potential to interact with other medications, and it’s crucial to be aware of these interactions to prevent adverse effects and ensure the medication’s efficacy. Some notable drug interactions include:

Erythromycin

A macrolide antibiotic like erythromycin can increase Acrivastine levels in the blood. This may enhance the antihistamine’s effects, leading to a higher risk of side effects. Caution and monitoring are advised when these medications are used concomitantly.

Ketoconazole

The antifungal medication ketoconazole may elevate Acrivastine concentrations in the body. This interaction could potentially increase the risk of side effects associated with Acrivastine. Healthcare professionals may consider dosage adjustments or alternative medications in such cases.

Sedatives and CNS Depressants

Concurrent use of Acrivastine with sedatives or central nervous system (CNS) depressants may lead to additive sedative effects. Caution is recommended, especially in activities requiring mental alertness, to avoid excessive drowsiness.

Proper dosage of Acrivastine is vital to achieving optimal relief from allergy symptoms while minimizing the risk of side effects. The recommended dosage depends on the individual’s age and medical condition. Always follow the guidance of a healthcare professional for accurate dosing.

Adults and Children over 12 years:

Initial Dose

For adults and children over 12 years, the recommended starting dose of Acrivastine is 8-12 mg, taken every 4-6 hours as needed. This initial dose is designed to provide prompt relief from allergy symptoms, including sneezing, itching, and nasal congestion.

Maximum Daily Dose

The maximum allowable daily dose for adults and individuals over 12 years is 24 mg within a 24-hour period. It’s crucial to adhere to this limit to avoid potential side effects and ensure the medication’s effectiveness. This dosage regimen allows flexibility for individuals to take Acrivastine as required throughout the day while staying within the recommended daily limit.

Children 6-12 years

Initial Dose

Children between 6 and 12 years of age are typically prescribed an initial dose of 4-8 mg. This dose should be taken every 4-6 hours as necessary, aligning with the onset of allergy symptoms. The aim is to provide relief while minimizing the risk of side effects in this age group.

Maximum Daily Dose

The maximum daily dose for children aged 6-12 years is 16 mg within a 24-hour period. This dosage limitation is important for ensuring the safety of pediatric patients while still providing effective relief from allergy symptoms.

Acrivastine is available over-the-counter in many regions, allowing easy access for individuals seeking relief from allergy symptoms. However, it is advisable to consult a healthcare professional before starting any medication, especially for those with underlying health conditions or taking other medications.