• Treatment of Inflammatory Lesions: Amzeeq is primarily used to address the inflammatory lesions associated with non-nodular moderate to severe acne vulgaris, including papules and pustules.
• Age Range: Approved for patients as young as 9 years old, making it suitable for a wide range of individuals dealing with acne.
• Topical Application: Unlike oral medications, Amzeeq is applied directly to the affected skin areas, allowing for targeted treatment of acne lesions while minimizing systemic side effects.
• Minocycline Formulation: Amzeeq contains minocycline, a broad-spectrum antibiotic that targets the bacteria responsible for acne, particularly Propionibacterium acnes.
• Alternative to Oral Antibiotics: Offers an alternative for patients who may not tolerate or prefer to avoid oral antibiotics due to gastrointestinal side effects or antibiotic resistance concerns.
• Convenient Application: The foam formulation allows for easy and convenient application, making it suitable for daily use as part of a skincare routine.
• Reduction of Lesions: Clinical studies have demonstrated the effectiveness of Amzeeq in reducing the number and severity of acne lesions, leading to improvements in overall skin appearance and quality of life.
• Adjunctive Therapy: Can be used alone or in combination with other acne treatments, such as topical retinoids or benzoyl peroxide, depending on the individual’s needs and treatment plan.
• Long-Term Management: Provides a long-term management option for individuals with chronic or recurrent acne, helping to prevent the formation of new lesions and maintain clear skin over time.

• Minocycline Action: Amzeeq works by utilizing minocycline, a broad-spectrum antibiotic that targets the bacteria associated with acne, particularly Propionibacterium acnes. This bacterium contributes to the inflammation and formation of acne lesions.
• Anti-inflammatory Properties: In addition to its antibiotic effects, minocycline also possesses anti-inflammatory properties. It helps to reduce the inflammatory response within the skin, which is a key factor in the development of acne lesions.
• Topical Application: Amzeeq is formulated as a topical foam, allowing for direct application to the affected skin areas. This targeted delivery minimizes systemic exposure while maximizing efficacy at the site of action.
• Foam Formulation: The foam formulation of Amzeeq facilitates penetration of the minocycline into the skin, ensuring effective distribution throughout the affected areas.
• Reduction of Lesions: By targeting both the bacteria and inflammation associated with acne, Amzeeq helps to reduce the number and severity of inflammatory lesions, including papules and pustules.
• Continuous Treatment: Continuous use of Amzeeq is recommended to maintain its therapeutic effects and prevent the recurrence of acne lesions. Consistency in application is essential for achieving optimal results in acne management.

Common Side Effects:

• Skin irritation: Mild to moderate skin irritation, such as redness, itching, or dryness, may occur at the application site.
• Discoloration: Temporary skin discoloration, including hyperpigmentation or hypopigmentation, may occur, especially in individuals with darker skin tones.
• Photosensitivity: Increased sensitivity to sunlight and UV radiation, leading to sunburn or sun sensitivity reactions.
• Oily skin: Some individuals may experience an increase in skin oiliness or shine.

Serious Side Effects:

• Allergic reactions: Rare but serious allergic reactions, including rash, swelling, or difficulty breathing, may occur. Immediate medical attention is necessary if any signs of an allergic reaction develop.
• Pseudotumor cerebri: In rare cases, minocycline, the active ingredient in Amzeeq, may cause intracranial hypertension or pseudotumor cerebri, characterized by symptoms such as severe headache, vision changes, or nausea.
• Gastrointestinal effects: Although less common with topical administration, gastrointestinal side effects such as nausea, vomiting, or diarrhea may occur.
• Superinfection: Prolonged or inappropriate use of antibiotics like minocycline may lead to the development of secondary infections caused by resistant bacteria or fungi.

• Avoid contact with eyes, mouth, and mucous membranes during application.
• Use sunscreen and protective clothing to minimize sun exposure due to increased photosensitivity.
• Discontinue use and consult a healthcare provider if severe skin irritation or allergic reactions occur.
• Use with caution in individuals with a history of intracranial hypertension or liver dysfunction.
• Do not use it in combination with other acne medications containing benzoyl peroxide or retinoids without consulting a healthcare professional.

• Topical Preparations: Avoid using other topical acne medications containing benzoyl peroxide or retinoids concurrently with Amzeeq unless directed by a healthcare professional to prevent potential interactions or increased skin irritation.
• Oral Medications: Inform healthcare providers about any concurrent use of oral medications, particularly other antibiotics or medications metabolized by the liver, to assess for potential drug interactions.
• Antacids and Supplements: Avoid taking antacids, iron supplements, calcium supplements, or multivitamins containing minerals within 2 hours before or after using Amzeeq, as these products may interfere with the absorption of minocycline.
• Blood Thinners: Use caution when combining Amzeeq with blood thinners (e.g., warfarin) due to the potential for increased bleeding risk. Regular monitoring of blood clotting parameters may be necessary.
• Oral Contraceptives: Minocycline may reduce the effectiveness of oral contraceptives, increasing the risk of unintended pregnancy. Consider using alternative or additional methods of contraception during treatment with Amzeeq.
• Alcohol: While there are no specific interactions between alcohol and Amzeeq, excessive alcohol consumption may exacerbate certain side effects, such as dizziness or gastrointestinal upset. Drink alcohol in moderation or as advised by healthcare providers.

• Apply a thin layer of Amzeeq foam to the affected areas of the skin once daily, preferably in the evening, after cleansing and drying the skin.
• Dispense an amount of foam sufficient to cover the entire affected area with a pea-sized amount for each facial region (e.g., forehead, chin, nose, each cheek).
• Gently massage the foam into the skin until it is absorbed, avoiding contact with eyes, mouth, and mucous membranes.
• Use consistently as directed by a healthcare professional to achieve optimal results in acne management.
• Consult a healthcare provider for dosage adjustments or additional guidance if needed.

• Amzeeq is a prescription medication and is not available over-the-counter.
• A healthcare provider, such as a dermatologist or primary care physician, must prescribe Amzeeq after evaluating the patient’s medical history and determining the appropriateness of treatment.
• Patients should follow their healthcare provider’s instructions regarding the dosage, duration, and application of Amzeeq.
• Regular follow-up appointments may be necessary to monitor treatment progress and assess for any side effects or adverse reactions.
• Do not use Amzeeq without a prescription, and consult a healthcare professional for any concerns or questions about its use.

1. What is Amzeeq?

Amzeeq is a topical formulation of minocycline used primarily to treat acne. It is designed to be applied directly to the skin.

2. How does Amzeeq work?

Amzeeq works by reducing inflammation and killing bacteria that contribute to acne. It also helps to prevent new acne lesions from forming.

3. What are the main ingredients in Amzeeq?

The main active ingredient in Amzeeq is minocycline, which is an antibiotic. The formulation may also include other excipients for stability and skin absorption.

4. Who can use Amzeeq?

Amzeeq is typically prescribed for individuals aged 9 years and older who suffer from inflammatory acne.

5. How is Amzeeq applied?

Amzeeq is applied as a thin layer to the affected areas of the skin once daily. It’s important to follow the application instructions provided by a healthcare provider.

6. Are there any side effects associated with Amzeeq?

Common side effects may include skin irritation, dryness, or itching at the application site. More serious side effects can occur but are less common.

7. Can Amzeeq be used in combination with other acne treatments?

Yes, Amzeeq can be used alongside other topical or systemic acne treatments, but it’s best to consult a healthcare provider for personalized advice.

8. How long does it take to see results from Amzeeq?

Most users may begin to see improvement in their acne within 12 weeks of consistent use, but individual results can vary.

9. Is Amzeeq safe for all skin types?

Amzeeq is generally safe for all skin types; however, individuals with specific sensitivities should consult a healthcare professional before use.

10. Can pregnant or breastfeeding women use Amzeeq?

Pregnant or breastfeeding women should consult their healthcare provider before using Amzeeq, as the effects on pregnancy and lactation are not fully established.

11. What should I avoid while using Amzeeq?

Avoid using harsh skin products, such as scrubs or exfoliants, and direct sun exposure, as they could increase skin irritation.

12. How should Amzeeq be stored?

Amzeeq should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.

13. What happens if I miss a dose of Amzeeq?

If you miss a dose, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed one and resume your regular schedule.

14. Is a prescription required for Amzeeq?

Yes, Amzeeq is a prescription medication and should be used under the guidance of a healthcare provider.

15. Can I use Amzeeq on my entire face?

Amzeeq can be applied to the affected areas of the face but should not be applied over large areas of skin unless directed by a healthcare provider.

16. What should I do if I experience severe side effects?

If you experience severe side effects, such as unusual swelling or difficulty breathing, seek medical attention immediately.

17. Will using Amzeeq cause my acne to get worse before it gets better?

Some users may experience an initial worsening of acne as the product decreases inflammation and irritation; this is usually temporary.

18. Can Amzeeq cause photosensitivity?

While Amzeeq is less likely to cause photosensitivity than other acne medications, it is still advisable to use sunscreen and protective clothing when outdoors.

19. How long can I use Amzeeq?

Your healthcare provider will provide specific guidance, but it can be used until the treatment goals are achieved, often up to 12 weeks or longer with medical advice.

20. Is Amzeeq effective for all types of acne?

Amzeeq is primarily effective for inflammatory acne (such as pustules) but may be less effective for non-inflammatory acne (such as blackheads).