| Common Brands | Aristada Injection |
|---|---|
|
Drug Class |
Atypical Antipsychotics |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Prescription only |
Aristada Injection is an antipsychotic medication indicated for the treatment of schizophrenia in adults.
It uses aripiprazole lauroxil as its active drug component, which is an injectionable form of aripiprazole administered in a depot form.
Aristada is useful in the treatment of schizophrenia by managing symptoms such as delusions, hallucinations and disorganized thoughts.
Aristada is given in the form of an injection administered by a health care provider.
The injection is a muscle injection also known as intramuscular injection. The injection is usually administered in the deltoid (upper arm) or gluteal (buttock) muscle
The injection is often done once every 30 days although the actual frequency will vary depending on what your doctor prescribes.
Some patients can be on Aristada every six weeks or even two months, as per their needs and treatment effectiveness
Aristada’s mechanism of action consists of altering the balance of certain chemical agents in the body, mainly dopamine and serotonin.
These neurotransmitters play a pivotal role in the manifestation of emotions and cognition.
Aristada, among other drugs, helps to improve the negative side effects of schizophrenia by restoring the balance of these chemical agents in the patient’s brain
Every medication, including Aristada, carries with it the possibility of adverse effects. The following are the more frequently observed side effects:
More severe side effects can also present themselves although they are more infrequent. These entail:
There course shall be some key cautions that must be observed when handling Aristada that include:
This calls for vigilance especially during the initial phases of treatment or whenever the dose is modified.
. Activity requiring complete alertness such as driving should not be performed until the patients knows how to cope with the effects of the medication..
CYP3A4 inhibitors, like ketoconazole and clarithromycin, may increase the levels of Aripiprazole. Aristada needs to have their dose reduced.
CYP2D6 inhibitors, such as fluoxetine and paroxetine, also elevate the plasma concentration of Aripiprazole. They may require dosage adjustments.
CYP3A4 inducers, such as carbamazepine and rifampin, may decrease the levels of Aristada, thereby reducing its effects. The dose may need to be upped.
CNS Depressants
Combining Aristada with CNS depressants, such as alcohol, benzodiazepines, or opioids, can increase sedative effects and CNS depression, thus it needs to be used cautiously.
Antipsychotic Drugs:
The use of Aristada in combination with other antipsychotics or dopamine antagonists can lead to increased risk of EPS, sedation, or NMS.
Neuroleptic Malignant Syndrome (NMS):
Use of Aristada in combination with other dopamine antagonists can increase the risk of NMS. NMS is a potentially life-threatening neurologic reaction.
These interactions should be watched carefully during Aristada treatment, especially when used in conjunction with CYP450 inhibitors/inducers or CNS depressants.
The Aristada dosage may differ based on the specific patient and the degree of his or her symptoms. However, a common dosing regimen is as follows:
The specific dose and schedule may vary in accordance to the patient’s condition, treatment history and the prescribing physician’s opinion.
It is recommended that the prescribed dosing schedule be adhered to and that doses be taken in full as this will ensure a positive outcome.
Aristada Injection is a medication that is available only through a prescription. This indicates that it can only be ordered by a qualified professional like a physician or a psychiatrist.
A healthcare provider would check the medical history and health status of the individual and the medications they are taking before prescribing Aristada to the patient
. Aristada should not be sought out by any patient in the absence of a prescription because such a practice is dangerous and it needs to be taken only when prescribed by a professional in order to avoid the risks associated with taking incorrect dosages of the drug.
Aristada Injection is a long-acting injectable antipsychotic used for the treatment of schizophrenia in adults.
Aristada works by affecting the balance of certain chemicals in the brain, particularly dopamine and serotonin, which helps to control symptoms of schizophrenia.
Aristada may be suitable for adults diagnosed with schizophrenia who may benefit from a long-acting injection rather than daily oral medication.
Aristada is administered as an intramuscular injection, typically by a healthcare professional, usually in the buttock or upper arm.
Aristada is available in various dosing options, including 441 mg, 662 mg, and 882 mg, with administration intervals of 4 to 8 weeks depending on the dose.
Depending on the prescribed dose, Aristada injections are typically given every four to eight weeks.
Common side effects can include drowsiness, weight gain, insomnia, anxiety, and injection site reactions.
Yes, serious side effects may include tardive dyskinesia, neuroleptic malignant syndrome, or increased risk of metabolic syndrome.
It’s important to consult a healthcare provider, as Aristada can interact with other medications, particularly other central nervous system depressants.
The safety of Aristada during pregnancy and breastfeeding is not well established, so it should only be used if clearly needed and prescribed by a doctor.
While its primary indication is schizophrenia, it may also aid in managing symptoms related to other mental health conditions, though this is more off-label use.
Ensure that you inform your healthcare provider of any medications you’re taking and your full medical history before the injection.
Contact your healthcare provider for guidance on rescheduling the missed injection as soon as possible.
Tapering off Aristada under a doctor’s supervision is important to minimize potential withdrawal symptoms or exacerbation of psychotic symptoms.
The effects of Aristada can last several weeks, depending on the administration schedule and individual factors.
Seek immediate medical attention if you experience severe side effects such as chest pain, difficulty breathing, or signs of an allergic reaction.
Coverage for Aristada may vary by insurance plan, so it’s best to check with your insurance provider for details on coverage and costs.
Yes, weight gain can be a common side effect; therefore, monitoring weight and diet is important during treatment.
Aristada is typically administered in a clinic or hospital setting, so you will need to see a healthcare provider for injections.
Aristada should be stored in a refrigerator but can be kept at room temperature for a short period before use. Always follow your healthcare provider’s guidance for storage.
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