With the usual dose and dosage regimen, Armour Thyroid is expected to have optimal effects when taken orally, daily, on an empty stomach, at least 30 to 60 minutes prior to food intake,
if any, for appropriate absorption of the medication. Armour Thyroid is sold in pharmacy shops as tablets, and the amount to be taken will depend upon growth age, weight, the levels of thyroid hormones in the body, and how severe the hypothyroidism is among the patients.
General Dosage Guidelines:
- Initial Dose: For most adults, the starting dose of Armour Thyroid is generally 30 mg to 60 mg once daily.
- Adjustment: The dosage may be adjusted based on regular monitoring of thyroid hormone levels (T3, T4, and TSH). The objective is usually attenuation of hypothyroidism symptoms and restoration of normal parameters of Thyroid Stimulating Hormone (TSH) levels.
Armour Thyroid is indicated for hypothyroidism, or underfunctioning of the thyroid gland, due to a lack of thyroid hormone required for normal bodily activities. Hypothyroidism is characterized by the thyroid gland’s failure to secrete sufficient levels of T4 and T3 hormones leading to symptoms such as tiredness, appetite increase, depression, and skin cracking.
- T4 (levothyroxine sodium) is an inactive pro hormone which gets bioactivated to T3 (Thyroid Triiodothyronine) done in the liver and other sites. T3 is the active form of the thyroid hormone that controls the metabolism of all cells in the body.
- Armour Thyroid contains both T4 and T3 hormones hence replenishing the deficiency of both hormones in the body. It is believed that T4 and T3 combination is more effective than the latter which is only T4, as it more promotes the body’s normal thyroid activity.
- As with every drug, it is possible that Armour Thyroid may lead to some adverse reactions.
Side Effects Found Often:
- Heartbeats that are faster than usual (tachycardia)
- A feeling of nervousness or pressure (anxiety)
- Difficulty in falling or remaining asleep (insomnia)
- The feeling of pain in the head (headache)
- Heat intolerance and associated or unassociated increase in sweating
- Uncontrolled shaking (tremors)
• Alteration in levels of desire for food (appetite)
Anticoagulants:
Armour Thyroid may enhance the action of anticoagulants such as warfarin, thus increasing the risk of bleeding. This is because thyroid hormones can increase the metabolism of clotting factors. Blood clotting parameters (INR) should be monitored regularly when using these drugs together Antidiabetic Drugs:
Iron Preparations:
Iron supplements or other multivitamins containing iron interfere with the absorption of Armour Thyroid. One is, therefore, advised to keep at least a gap of 4 hours before giving a thyroid hormone and iron together since it may affect the performance of thyroid hormones.
Calcium Supplements:
Calcium supplements, specifically calcium carbonate, interfere with the absorption of thyroid hormone medicines. Therefore, taking Armour Thyroid and calcium should be timed at different hours.
Digoxin:
Digoxin is a heart drug. Its effect might be modified in patients receiving thyroid replacement therapy. The level of digoxin might become low due to the increase in thyroid hormone levels. Its dosage may need to be altered.
Corticosteroids:
Corticosteroids, such as prednisone, can interact with the replacement therapy for thyroid hormone, and thus thyroid hormone levels may decrease. Patients who are on corticosteroids may need to adjust the dose of thyroid replacement drugs.
Sympathomimetic Medications:
Medications such as pseudoephedrine, a decongestant, and other sympathomimetics can enhance the cardiovascular side effects of Armour Thyroid, for example, tachycardia and hypertension. This combination requires careful use.
Anticonvulsants:
Some anticonvulsants like phenytoin and carbamazepine may enhance the metabolism of thyroid hormones. Thus, the efficacy of Armour Thyroid may be reduced and its dose increased.
It is essential to advise your doctor of any other medications or supplements you take before beginning Armour Thyroid to avoid potential interactions. Maintenance of regular monitoring of the thyroid levels is essential to readjust the dosage and for optimal treatment.
The particular dosage of Armour Thyroid prescribed will depend on a number of different individual factors including but not limited to: the age of the patient, weight, levels of thyroid hormones in the body and the extent of the condition.
Common Dosing Schedule:
- Initial Dose: Often starts at 30 mg to 60 mg daily
- Maintenance Dose: Most patients maintain a dose of 60 mg to 120 mg on a daily basis although some individuals may need higher or lower doses based on their own responses to the medication.
Armour Thyroid is a prescription medication in that it cannot be dispensed without a physician‘s order. Your health care provider will evaluate your signs and symptoms, carry out appropriate investigations (for example, blood tests to evaluate the level of thyroid hormones), and decide whether Armour Thyroid is suitable for you. Thyroid levels have to be monitored regularly in order to determine that the correct dosage is administered and to prevent complications attributed to either over or under replacement therapy.