Artiss Duo Set is a medical device that is clindamycin and must therefore be utilized in a clinical or surgical environment by professional health caregivers only. The following is a basic guideline for its application:
- sanitaion: Prior to the use of the Artiss Duo Set, a preparatory step is performed by the surgeon to the operative field, making certain that the tissues are free of any contaminants or infectious agents.
- Mixing the Components: The two elements (fibrinogen and thrombin) are kept separated and joined together just prior to use. There is a strict process for carrying out the mixing to obtain the best results.
3. Application: The combined fragments are placed to the surgery site using an applicator. Fibrinogen and thrombin are usually misted or dripped on the area of the wound.
The working principle of Artiss Duo Set is like that of the body’s own wound-healing process. Firstly, it triggers a series of events in the wound that lead to clotting and its associated advantages:
- Fibrin clot formation: Fibrinogen and thrombin are placed on the wound whereby healing occurs. In this instance, thrombin activates fibrinogen, which is transformed into fibrin. The somewhat sculptural molecules of fibrin interlace and form netting that serves the purpose of a clot covering Hence the wound or surgical cut is filled with a clot.
- Sealant properties: This clot functions as a proper shield seal, minimizing the seepage of-oriented fluids, averting excess bleeding and provision of cover over the wound.
• Biocompatibility: The materials of Artiss Duo Set are made from human blood materials and they undergo treatment to minimize the chances of infection throughout the manufacturing process
As with any pharmaceutical solution, the Artiss Duo Set has a likelihood of experiencing side effects, although most cases are mild and infrequent.
Some of the potential side effects consist of:
- Infection: Even though the device is meant to minimize the chances of contracting an infection, improper use or contamination during the preparation of the device can results in infection.
- Thrombosis: There is a risk of thrombosis (blood clot formation at an undesired site that can lead to complications such as occlusion of a blood vessel) when the fibrin sealant is misplaced or misapplied.
• Tissue Necrosis: In some instances, when misuse occurs, the patient may experience either impaired healing, or in the worst instance, tissue loss (death of tissues) if the tissue adhesive is overused or misused.
The Artiss Duo Set is safe to use but certain precautions have to be taken:
- Allergy History: This product should not be used in known human blood product allergic patients or people allergic to any of the components found in the fibrinogen and thrombin combination.
- Not for Use in Large Body Cavities: The Artiss Duo Set should not be placed in large body cavities like those present in the abdomen or thorax as this may require extra surgical procedures.
•Application to Infected or Contaminated Tissue: The sealant should be refrained from using on already infected or dirty tissue to prevent deterioration or adverse effects of healing.
Anesthesia interactions: Artiss Duo Set, which is used as a tissue adhesive, should be used cautiously alongside local anesthetics or general anesthesia as the combined effects may alter tissue response or healing time. Always inform your healthcare provider about any anesthesia being administered during the same procedure.
Anticoagulant medications: Patients on anticoagulants (e.g., warfarin, heparin) may experience altered wound healing or increased bleeding risk when using Artiss Duo Set. It’s important to discuss any blood-thinning medications with your healthcare provider prior to use.
Immunosuppressive drugs: Artiss Duo Set should be used with caution in individuals taking immunosuppressive drugs as these may affect the body’s response to the adhesive and increase the risk of infections or delayed wound healing.
Steroids: The use of steroid medications can potentially interfere with the healing process. If you are on steroids, your healthcare provider should be consulted about the potential impact on the use of Artiss Duo Set.
Topical antiseptics or other adhesives: Avoid using other adhesives or antiseptic treatments on the wound area treated with Artiss Duo Set, as these may interfere with the adhesive’s bond or irritate the skin. Always follow the post-treatment instructions provided by your healthcare provider.
As stated, the Artiss Duo Set is a surgical utility and hence not controlled by any standard dosage guidelines. Dosage of the fibrinogen and thrombin used, however, does vary with the size and difficulty of the surgical site.
The healthcare professional will ascertain the specific amount required from the patient’s individual requirements.Typically, the application will be customized for each surgical procedure. Surgeons will apply the appropriate amount based on their experience and the requirements of the surgery.
The Artiss Duo Set is a prescription-only medicinal device which can be dispensed and used only by licensed healthcare providers in a clinical or surgical environment.
This ensures that the product is used in a proper way and that appropriate expertise is available to manage any complications that may arise.