Astelin Nasal Spray is normally administered by means of nasal inhalation. The standard dose for adults and patients of older than 12 years is usually stated as 1 or 2 sprays to each nostril one to two times a day as needed based on symptoms. Nevertheless, particularized instructions will be given depending on the condition of the patient, hence it is crucial to adhere to the instructions of the prescribing clinician or the guidelines on the medicine container.
- Before using the nasal spray: Gently shake the bottle. To prepare for use, activate the spray by pressing down on the pump a few times until a fine mist is emitted (this is applicable if you have not used the spray for a few days or it is your first time using the spray).
- Positioning: Slightly bow your head forward, insert the pointed tip into one nostril and spray the medicine as directed. Gently inhale as you spray to ensure that the spray reaches the nasal cavity.
• Post-application: After use of the spray, do not blow the nose at once to facilitate the effectiveness of the drug.
Astelin functions by aiming at and antagonizing H1 histamine receptors in the nose and the nasal cavity. When the immune system finds perceives a particular allergen (like pollen, dust, pet furs or feathers), histamine is secreted. This results to typical allergic symptoms such as itching, sneezing, blockage of the nares, and excess mucus production.
- The azelastine (active component) is a selective Antihistamine, which means that is attaches to those tissue specific receptors in the nose to inhibit histamine action and thus the result of allergy symptoms.
- Local Action: As Astelin is a nasal spray, it is effective in alleviating nasal congestion, sneezing and running nose signs and symptoms very quickly and at the effective site.
As with any other medication, Astelin Nasal Spray may have side effects, though not everyone experiences them. Some common and less common side effects include:
- It is normal to report a strange taste in the mouth. A bitter or unpleasant taste in the mouth is one of the more common side effects of Astelin nasal spray.
- Nasal irritation. This may include dryness, burning, or stinging sensations in the nose and/or throat.
- Headache. Some users are prone to mild headaches after the use of the nasal spray.
- Drowsiness. Although azelastine is less sedative than first-generation antihistamines, some people can still feel drowsy.
- Sore throat; a side effect could also be a dry or scratchy throat.
- Allergic Reaction to Azelastine: If you experience allergy to azelastine or any of the constituents of the nasal spray, Astelin should not be used. Be sure to inform your doctor of all known allergies prior to beginning treatment with any new medication.
- Pregnancy, Astelin and Breastfeeding: The use of Astelin during pregnancy is C according to the classification of drugs for use in pregnancy, which means that the use of this drug in this condition has not been determined. It should be used during pregnancy but only when absolutely necessary and on the advice of a doctor. Azelastine is also breast milk excreted, thus it is better to refrain from the use of the drug while breastfeeding.
• Eye Irritation: Avoid spraying the nasal spray into the eyes as it may cause irritation. Do not attempt to spray it in the eyes, and in the event that contact is made with the eyes, wash the eyes with plenty of water.
Astelin (azelastine hydrochloride) is an antihistamine nasal spray used to treat allergic rhinitis symptoms, such as sneezing, nasal congestion, and runny nose. Like any medication, it may interact with certain drugs, which could alter its effectiveness or increase the risk of side effects.
- CNS Depressants: When Astelin is used with other central nervous system (CNS) depressants, such as alcohol, benzodiazepines (e.g., lorazepam, diazepam), or sedatives, it may increase drowsiness or sedation. This could impair your ability to perform tasks that require full alertness, such as driving or operating machinery.
- Other Antihistamines: Concurrent use of Astelin with other oral or nasal antihistamines can intensify the sedative effects, leading to excessive drowsiness, dizziness, or dry mouth. It is advisable to avoid using multiple antihistamines together unless directed by a healthcare provider.
- Monoamine Oxidase Inhibitors (MAOIs): Combining Astelin with MAO inhibitors (e.g., phenelzine, tranylcypromine) can increase the risk of severe side effects, such as excessive drowsiness, hypotension, or other sedative effects, as MAOIs may alter the metabolism of antihistamines.
The appropriate dosage of Astelin depends on the patient’s age and condition being treated. Below are general dosage guidelines:
- Adults and Children over 12 years: The typical recommended dose is 1 or 2 sprays in each nostril twice a day (morning and evening). The total daily dose should not exceed 4 sprays per nostril per day.
- Children 6 to 12 years: The usual dose is 1 spray in each nostril twice daily. The dose may be increased if necessary, but the maximum recommended dose is 2 sprays per nostril per day.
- Children under 6 years: Astelin is generally not recommended for children under 6 years unless prescribed by a healthcare provider.
- Do not exceed the recommended dosage: Overuse of the nasal spray may lead to an increased risk of side effects like nasal irritation or bleeding.
- Avoid other nasal decongestants: If you are using other nasal sprays or decongestants, consult with your healthcare provider before combining them, as they could interact and cause adverse effects.
Nasal hygiene: If you experience nasal irritation, dry air, or congestion, consider using a humidifier or saline nasal spray in conjunction with Astelin to help keep the nasal passages moist.