| Common Brands | Avage (brand name no longer available) |
|---|---|
|
Drug Class |
Retinoid |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Prescription only |
Avage is a topical medication used to treat the skin condition, most notably photoaging, caused by long-term exposure to the sun, and keratosis pilaris, the condition characterized by small, rough bumps appearing on several sites that are usually in well-defined locations on the upper arms or thighs.
Avage is just a brand name for tazarotene, a drug that falls into the class of compounds known as retinoids, being essentially derivatives of vitamin A.
Retinoids are drugs that have the potential to affect the rate at which skin cells grow. They come in handy in managing several skin conditions, among them acne, psoriasis, as well as all manifestations of aging, including fine lines, wrinkles, and age spots
Avage is applied to the skin as a topical and must be used according to the directions from your physician or as stated on your prescription label.
Step 1: Clean the affected area: Start by washing the affected area with a mild soap and patting it dry with a towel.
Step 2: Place a thin layer: Place the Avage lotion with your fingertips just over the affected area. Please apply once a day in the evening, which should be applied in a thin layer to prevent irritation. Avoid applying it over areas where the skin is broken or irritated.
Step 3: Wash your hands: After application, wash your hands thoroughly to avoid transferring the medication to other parts of your body or face, especially sensitive areas like the eyes or mouth.
Avage is primarily an epidermal growth modifier: it acts on the outermost skin layer to accelerate the rate of turnover of skin cells. The medication functions by binding to certain receptors in skin cells known as retinoic acid receptors that modify gene expression responsible for the production of skin cells.
It accelerates the turnover process, thereby clearing pores, facilitating a reduction in wrinkles and fine lines, and rejuvenating skin texture
. This assists in reducing the appearance of skin discoloration and other marks such as hyperpigmentation and age spots, which occur due to sun damage. It also produces an anti-inflammatory effect, that may be exerted to manage diseases such as acne and keratosis.
Although Avage is very effective as a skin treatment medication, there are some potential side effects associated with taking this medication. Common side effects include:
Skin irritation: This is the most common adverse effect and may include redness, peeling, burning, and dryness. It’s much more likely to occur in the first stages of treatment or if you have sensitive skin.
Sun sensitivity: Avage increases your risk of sunburn. Using a sunscreen will be important both during treatment with Avage and afterwards to avoid UV damage to your skin.
Sensitivity: Sensitive skin types will find that they are more irritated in areas where the integrity of the skin has been compromised.
Pregnancy: Avage is contraindicated in pregnancy. Tazarotene constitutes a class of drugs that have been known to cause birth defects. Women who are pregnant or planning to conceive should not use Avage. Inform your doctor if you are pregnant or planning to conceive before you start on Avage.
Avoid mucous membranes: Apply Avage away from the eyes, mouth, and mucous membranes, where it may irritate the patient. If applied to any of these areas, rinse with water.
Skin conditions: Consult your doctor before using Avage if you have eczema, cuts, abrasions, or other skin problems because this medicine may worsen irritation.
Topical Retinoids: Combining Avage with other topical retinoids (e.g., adapalene, tretinoin) can increase the risk of skin irritation, redness, dryness, or peeling, as these medications may enhance the drying and exfoliating effects.
Corticosteroids: Using Avage with topical corticosteroids may reduce the effectiveness of tazarotene, as corticosteroids can interfere with the skin’s natural ability to renew and heal, potentially leading to skin thinning.
Photosensitizing Agents: Combining Avage with other photosensitizing medications (e.g., certain antibiotics like tetracyclines, or diuretics like furosemide) may increase the risk of sunburn or skin sensitivity, making it important to use sun protection.
Acne Treatments: When used together with oral or topical acne treatments (e.g., benzoyl peroxide), there may be an increased risk of skin irritation, redness, or dryness, so careful monitoring is needed to avoid excessive irritation.
The recommended adult dose for Avage is the application of a thin layer of the cream or gel to the affected area once daily at evening time.
However, individual and condition-specific variations may apply. To be sure, follow the instructions of your healthcare provider.
Start with a lower concentration: For sensitive skin or those new to using retinoids, your healthcare provider may recommend starting with a lower concentration or using the medication every other day to minimize irritation.
Avage is a prescription drug: It can not be bought over-the-counter, but only after your skin condition has been reviewed by a doctor.
More often than not, it is prescribed by a dermatologist for photoaging or keratosis pilaris; however, it may be prescribed by physicians for other types of skin conditions off-label, as well.
Before Avage can be prescribed for you, your doctor will assess your skin type, other drugs you are taking, and whether or not you have contraindications, such as pregnancy or sensitive skin.
What is Avage?
Avage is a prescription medication containing the active ingredient tazarotene, which is primarily used to treat acne and psoriasis.
How does Avage work?
Avage works by regulating skin cell production and promoting the turnover of skin cells, helping to unclog pores and reduce acne formation.
What are the common uses of Avage?
Avage is mainly used for treating acne vulgaris and psoriasis. It may also be effective for mild cases of photoaging.
What is the recommended application method for Avage?
Avage should be applied once daily to the affected areas of the skin, preferably in the evening after cleansing.
Are there any common side effects of using Avage?
Common side effects may include skin irritation, redness, peeling, dryness, and a burning sensation at the application site.
Can Avage be used in conjunction with other acne treatments?
Yes, but it’s important to consult a healthcare provider to avoid potential interactions or increased skin irritation.
How long does it take to see results from Avage?
Improvement in acne may take 4 to 8 weeks, but results can vary by individual. Consistent use is key for optimal results.
Is Avage safe for all skin types?
Avage may not be suitable for very sensitive skin. It’s advisable to consult a dermatologist before starting treatment.
Can pregnant women use Avage?
Avage is not recommended for use during pregnancy due to the potential risks to the fetus. Consult your doctor for alternatives.
What should I do if I miss a dose of Avage?
If you miss a dose, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule.
Can Avage cause skin discoloration?
Skin discoloration is not a common side effect, but some users may experience temporary changes. Consult a healthcare professional if concerned.
What should I avoid while using Avage?
Avoid excessive sun exposure, harsh skin products, and other retinoids without consulting a healthcare provider.
Can I use Avage if I have eczema or sensitive skin?
Avage may cause irritation for those with eczema or sensitive skin. It’s best to consult with a dermatologist before use.
How should Avage be stored?
Avage should be stored at room temperature, away from direct sunlight and moisture, and kept out of reach of children.
Is Avage a long-term treatment option?
Your healthcare provider may recommend long-term use based on your skin condition, but regular check-ups are important.
Does Avage expire?
Yes, like all medications, Avage has an expiration date. Check the packaging for the expiration date and do not use it after that time.
Can Avage be used on sensitive areas, like the face?
Avage can be used on the face, but care should be taken to avoid sensitive areas such as the eyes and mouth.
What is the mechanism of action of Avage?
As a retinoid, Avage works by modulating gene expression related to skin cell turnover and differentiation.
Are there special precautions for using Avage in combination with sunblock?
Yes, using a broad-spectrum sunscreen is highly recommended while using Avage to protect the skin from UV damage.
Where can I find more information about Avage?
More information can be found by consulting a healthcare provider or visiting reputable medical websites and resources.
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