Common Brands Ozobax, Ozobax DS, Fleqsuvy, Lyvispah, Lioresal (brand no longer available)
Drug Class
Muscle relaxant
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Prescription only
Allison Barnes, PharmD
Allison Barnes, PharmD
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Medically reviewed by Allison Barnes, PharmD last update on 20/12/2023


Baclofen, a medication with a history spanning over half a century, plays a significant role in the world of medicine. This comprehensive guide will delve deep into all aspects of Baclofen, from its origins and chemical structure to its diverse range of applications in the field of healthcare.

What is Baclofen?

Baclofen is a muscle relaxant and antispastic medication. It was first synthesized in the 1960s by Swiss scientists and later approved by the FDA in the United States for various medical conditions. It is classified as a gamma-aminobutyric acid (GABA) analogue, a neurotransmitter that inhibits nerve activity in the brain and spinal cord.

History and Development

Understanding the history of Baclofen provides insight into its discovery and evolution. This section will explore the origins of Baclofen and how it has become a staple in medical treatment.



Prescription only

Pregnancy & Lactation