Common Brands Wellbutrin XL, Wellbutrin SR, Forfivo XL
Drug Class
Atypical antidepressant
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Prescription only
Robert Chad Hakim, PharmD, BCCCP
Robert Chad Hakim, PharmD, BCCCP
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Medically reviewed by Robert Chad Hakim, PharmD, BCCCP last update on 20/12/2023


Bupropion is an antidepressant, unique for its chemical structure and mechanism. Originating as an atypical antidepressant, it is distinguished by its minimal effect on serotonin. The medication is primarily used to treat major depressive disorder and seasonal affective disorder, standing out for its low risk of sexual side effects and weight gain. 

Additionally, bupropion is effective in aiding smoking cessation. Its composition involves the inhibition of norepinephrine and dopamine reuptake, contributing to mood regulation. This dual action makes it a versatile option in mental health treatment and smoking cessation programs.



Prescription only

Pregnancy & Lactation