| Common Brands | Velivet, Caziant, Cesia (brand no longer available), Cyclessa (brand no longer available) |
|---|---|
|
Drug Class |
Estrogen / Progestin combined contraceptive |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Prescription only |
Caziant is a prescription medicine that contains fluticasone propionate as its active ingredient. It mainly serves in the treatment of inflammatory conditions, including asthma and allergic rhinitis. Caziant drugs fall under the category of corticosteroids. They are the type of medication that directly reduces inflammation, swelling, and irritation within the nasal passages and airways. For the most part, patients use Caziant by means of nasal spray and inhaler.
The active compound in Caziant, Fluticasone propionate, is an effective anti-inflammatory drug which decreases the symptoms of allergic reactions such as sneezing, runny nose, nasal congestion, and other symptoms that may be associated with this. Caziant has a therapeutic effect for individuals who suffer from chronic respiratory diseases, such as asthma and allergic rhinitis, by acting on the immune response that causes inflammation.
Caziant can be administered via a nasal spray or inhaler.
Nasal Spray (For Allergic Rhinitis)
Preparation:
Shake the nasal spray bottle gently before use.
Prime the spray by pressing the nozzle a few times until a fine mist appears. This is typically done the first time the spray is used or after it has not been used for a while.
Blow your nose gently to clear your nasal passages before using the spray.
Administration:
Close one nostril and insert the spray nozzle into the other nostril.
Close your mouth and breathe in gently as you spray the medicine into your nose.
If you need to spray medicine into the other nose, repeat the process.
After Use:
Wash the spray nozzle periodically to avoid clogging and infection.
Avoid snorting after spraying the medication since this can make the medicine go down the throat instead of staying in the nasal passage.
For the Inhaler (Asthma):
Preparation:
Remove the cap and shake the inhaler to ensure the medication is mixed well.
Hold the inhaler upright and exhale fully before using the inhaler.
Administration:
Place the mouthpiece in your mouth and close your lips around it.
Inhale deeply and press down on the inhaler to release the medication. Continue to breathe in slowly and deeply.
Hold your breath for a few seconds to allow the medication to settle in your airways.
Caziant works by acting on the immune system, thereby reducing inflammation in the airways and nasal passages due to allergies. This is how it works in different conditions:
Asthma: Asthma is a condition where the airways are inflamed and constricted, making breathing hard. The inflammation is caused mainly by an overreaction of the immune system to various stimuli, such as allergens or irritants. Fluticasone propionate, the active ingredient in Caziant, works by inhibiting the production of inflammatory mediators, including cytokines, histamines, and leukotrienes. This helps reduce airway inflammation and swelling, thereby making breathing easier for asthma patients.
Allergic Rhinitis: In allergic rhinitis, the nasal passages become inflamed due to an allergic reaction, usually to airborne allergens like pollen, dust, mold, or pet dander. The inflammation leads to symptoms like sneezing, congestion, and runny nose. Fluticasone propionate helps reduce inflammation in the nasal passages, reducing these symptoms and helping patients feel more comfortable.
By reducing inflammation, Caziant prevents the usual symptoms of both asthma and allergic rhinitis, making it a useful tool in the management of these chronic conditions.
Serious side effects, though rare, can be:
Immune system suppression that increases susceptibility to infection
Adrenal suppression particularly with long term use
Eye problems such as cataracts or glaucoma
Patients should report to their doctor any unusual signs and symptoms especially those associated with infection, hoarseness, or vision.
Infections: Caziant can suppress the immune system, making users more susceptible to infections. It is important to avoid exposure to individuals with infections and report any signs of infection to your doctor.
Adrenal Function: Prolonged use of corticosteroids like Caziant can affect adrenal gland function. Doctors may monitor adrenal function in long-term users.
Pregnancy and Breastfeeding: Caziant is to be prescribed during pregnancy only if its potential benefits outweigh the potential risks. Consult a physician before using the drug during pregnancy or breast-feeding.
Caziant may interact with other drugs, especially those that affect the metabolism of corticosteroids, including:
Ritonavir: This is an HIV drug that can increase the blood levels of fluticasone propionate, thus increasing the risk of side effects, such as suppression of the adrenal gland.
Ketoconazole: This is a potent antifungal that can also increase fluticasone levels and increase the risk of side effects.
Other Corticosteroids: Combination use of other corticosteroids with Caziant may lead to an increase in the risk of adverse effects, such as immunosuppression and adrenal suppression.
All medications taken by the patient, including over-the-counter drugs, vitamins, and herbal supplements, should be brought to the attention of their healthcare provider.
Asthma (Inhaler): 50 mcg per inhalation, given 2 times a day. The maximum amount per day is 100 mcg, 2 times per day.
Allergic Rhinitis (Nasal Spray): 1 spray per nostril, 1 time a day; the maximum number of sprays allowed per nostril in one day is 2 sprays.
Dosage adjustments may be carried out depending on the intensity of symptoms and patient’s response to the medication.
Caziant is available by a prescription from a doctor. There should be regular follow-ups with a healthcare provider so that the effectiveness of treatment can be monitored and side effects can be checked.
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