| Common Brands | Spectracef (brand no longer available) |
|---|---|
|
Drug Class |
Cephalosporin antibiotic |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Discontinued |
Cefditoren is an advanced third-generation cephalosporin antibiotic. It is specifically used in the treatment of bacterial infections. This third-generation cephalosporin antibiotic has a broader spectrum of activity and will work on a variety of bacterial pathogens, including those that are gram-positive or gram-negative. Cefditoren is administered orally but is used for the management of mild to moderate infections. Adults and children over a given age can use this to treat infections.
Cefditoren is administered orally with tablets. Doses range from two times a day as per the instructions given by the doctor about the required dosage and period of the medicine.
Take with food: Cefditoren should be taken with food to enhance its absorption and minimize the risk of gastrointestinal upset.
Do not crush or chew the tablet: The tablet should be swallowed whole to ensure proper absorption.
Complete the full course of treatment: Even if you start feeling better, it is essential to finish the entire prescribed course to prevent the infection from returning and to reduce the risk of antibiotic resistance.
If a dose is missed, it should be taken as soon as possible unless it is nearly time for the next dose. In that case, skip the missed dose and take the next one as scheduled.
Cefditoren is a beta-lactam antibiotic of the cephalosporin class. It works by inhibiting the synthesis of bacterial cell walls. Bacteria require their cell walls to maintain structural integrity. Cefditoren binds to specific proteins on the bacterial cell surface (penicillin-binding proteins or PBPs), interfering with the bacteria’s ability to build and maintain the cell wall. Due to this, the bacteria cannot survive, and they die out eventually.
Cefditoren is known to have broad spectrum activity in gram-positive as well as gram-negative bacteria. The drug is found to be effective against a wide variety of strains of Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Escherichia coli, and Moraxella catarrhalis. It can be ineffective for the resistant bacteria such as methicillin-resistant Staphylococcus aureus or MRSA.
Most patients tolerate cefditoren well, but as with all medications, it can cause side effects. Common side effects include:
Gastrointestinal side effects: These include nausea, diarrhea, vomiting, and abdominal pain. If these symptoms persist, it’s best to visit your doctor.
Rash or itching: A minor rash or itchy can occur in some people; this is a sign of an allergic reaction.
Headache: Some people are likely to experience this effect.
Yeast infections: Like most antibiotics, this drug throws off the normal balance between bacteria and fungi in the body and may result in yeast infections like thrush or vaginal yeast infections.
Severe allergic reactions: Although rare, cefditoren can cause anaphylaxis or other serious allergic reactions. Symptoms may include swelling of the face, lips, or throat, and difficulty breathing.
You should seek immediate medical attention if you experience severe side effects or signs of an allergic reaction.
Cefditoren can cause allergic reactions due to a history of cephalosporins and penicillin allergies. If this is your case, tell your doctor about it.
Kidney disease: You should inform your doctor that you have kidney disease in case he or she changes the amount you use to avoid adverse effects associated with the accumulation of drug in the body.
Pregnancy and lactation: Cefditoren is classified as a pregnancy category C drug. Therefore, its use should be made only if the benefits are considered to outweigh the risks. It is also excreted in breast milk; thus, it should be used cautiously in breastfeeding mothers.
Clostridium difficile-associated diarrhea (CDAD): As with all antibiotics, cefditoren can lead to CDAD, a condition that is characterized by severe diarrhea caused by an overgrowth of Clostridium difficile in the gut.
Probenecid: This drug prolongs the elimination of cefditoren from the body, causing high levels of blood and probably increasing the side effects.
Aluminum- or magnesium-based antacids: They reduce the absorption of cefditoren, and this may reduce the effectiveness of the drug.
Iron supplements: Concomitant use of iron supplements will decrease the absorption of cefditoren from the gastrointestinal tract.
Remind your physician if you are taking other prescription as well as nonprescription medicines, including vitamins, and herbal supplements.
The standard adult dosage of cefditoren is usually 200 mg to 400 mg taken twice daily, depending on the infection being treated. The exact dosage and duration of treatment will vary based on the infection, age, and overall health of the patient.
For children, the dosage is typically based on their weight and the severity of the infection, and the treatment duration can range from 5 to 14 days.
Patients with renal impairment may require a dosage adjustment to avoid accumulation of the drug in the body, which may increase the risk of side effects.
Cefditoren is a prescription-only medication. It is very important that a healthcare provider assess your condition and determine whether cefditoren is the appropriate antibiotic for your infection.
Before prescribing cefditoren, the healthcare provider will consider factors such as the type of infection, bacterial susceptibility, and any other medical conditions you may have.
Furthermore, because of concerns about antibiotic resistance, cefditoren should only be used for confirmed bacterial infections that are sensitive to the drug. Misuse of antibiotics can lead to resistance, rendering them less effective in the future.
Cefditoren should be taken exactly as prescribed and its full course of treatment to ensure that the infection has been completely eradicated as well as reducing the risks of bacterial resistance. Call your healthcare provider if any side effects or allergic reactions occur.
Cefditoren is a third-generation oral cephalosporin antibiotic.
It treats respiratory tract infections, skin infections, and community-acquired pneumonia.
It kills bacteria by inhibiting cell wall synthesis.
No, it only works against bacterial infections.
Oral tablets.
Generally 200 mg twice daily, depending on infection.
It’s usually prescribed for adults; pediatric use depends on doctor’s recommendation.
Diarrhea, nausea, headache, and rash.
Yes, especially in people allergic to penicillins or cephalosporins.
Yes, to fully clear the infection and prevent resistance.
Yes, taking it with food improves absorption.
Antacids and iron supplements may reduce its absorption.
Use only if clearly needed and prescribed by a healthcare provider.
Dose adjustment may be needed in severe kidney impairment.
Symptom improvement usually occurs within a few days.
Yes, like other antibiotics, it may cause diarrhea.
Store tablets at room temperature, away from moisture and heat.
Take it as soon as you remember unless it’s near the next dose.
Yes, it is sometimes prescribed for sinusitis.
Inform about allergies, other medications, pregnancy, and kidney problems.
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