Chlophedianol, Dexchlorpheniramine, and Pseudoephedrine

Common Brands Toplexil-D, Claridex-P, Alcoldex
Drug Class
Cough suppressant + Antihistamine + Decongestant
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Prescription only
Allison Barnes, PharmD
Allison Barnes, PharmD
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Medically reviewed by Allison Barnes, PharmD last update on 20/12/2023

Overview

Chlophedianol, Dexchlorpheniramine, and Pseudoephedrine are commonly combined in over-the-counter medications designed to treat symptoms associated with colds, allergies, and upper respiratory tract infections. This combination offers relief from a range of symptoms such as nasal congestion, sneezing, runny nose, and coughing.

The active ingredients in this combination medication work synergistically:

  • Chlophedianol: An antihistamine and cough suppressant (antitussive), which reduces histamine-induced allergic symptoms and helps suppress coughing.
  • Dexchlorpheniramine: An antihistamine that targets symptoms like sneezing, runny nose, and itching.
  • Pseudoephedrine: A decongestant that constricts blood vessels in the nasal passages to reduce swelling and alleviate nasal congestion.

This combination is available in various forms, including tablets, syrups, and liquid preparations, and provides comprehensive relief from the discomfort caused by colds, allergies, or respiratory infections.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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