Chlorcyclizine and Phenylephrine

Common Brands Duravent PE, among others
Drug Class
Antihistamine and Decongestant combination
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Over-the-counter (OTC) and prescription (varies by formulation)
Kristianne Hannemann, PharmD
Kristianne Hannemann, PharmD
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Medically reviewed by Kristianne Hannemann, PharmD last update on 20/12/2023

Overview

Chlorcyclizine and Phenylephrine are two medications often combined to treat a variety of symptoms related to allergies, colds, and other respiratory conditions. Chlorcyclizine is an antihistamine, while Phenylephrine is a decongestant. Together, they work to relieve symptoms like sneezing, runny nose, and congestion, making them commonly used in over-the-counter cold and allergy medications.

While they can be very effective, it’s important to understand how these medications work, how to use them properly, and the potential side effects or precautions associated with their use.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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