Chlorpheniramine and codeine is typically available in syrup or tablet form. The exact dosage will depend on the form you are using and your healthcare provider’s instructions.

• Syrup: For adults, the usual dose is 1 teaspoon (5 mL) of syrup every 4 to 6 hours, not exceeding the prescribed daily dose. For children, the dosage will vary based on age and weight, and it’s essential to follow the doctor’s recommendation.
• Tablets: If taking tablets, swallow them whole with water. The usual dose is one tablet every 4 to 6 hours, up to the prescribed limit.

Do not exceed the prescribed dosage. If you miss a dose, take it as soon as you remember, but skip the missed dose if it’s almost time for your next dose. Do not double the dose to make up for a missed one.

• Chlorpheniramine: As an antihistamine, chlorpheniramine works by blocking the effects of histamine, a substance released by the immune system during allergic reactions. Histamine causes symptoms like sneezing, itching, and a runny nose, and by blocking its action, chlorpheniramine helps to reduce these symptoms.
• Codeine: Codeine is an opioid that works centrally in the brain by inhibiting the cough reflex. It reduces the frequency and severity of coughing by acting on specific areas of the brain responsible for controlling coughing. It also has mild analgesic (pain-relieving) properties, which can further help in managing discomfort associated with a cold or flu.

When combined, chlorpheniramine and codeine provide a comprehensive solution to relieve allergy-related symptoms (such as sneezing and congestion) and reduce a persistent cough, offering relief to patients suffering from upper respiratory conditions.

While chlorpheniramine and codeine can be effective for managing cold and allergy symptoms, they may also cause side effects. Common side effects include:

• Drowsiness: Both chlorpheniramine and codeine can cause drowsiness or sedation. This is one of the reasons the medication is often recommended for use at night or in cases where the individual does not need to be alert.
• Dry Mouth: Chlorpheniramine, like many antihistamines, can reduce saliva production, leading to dry mouth.
• Dizziness or Lightheadedness: Some individuals may feel dizzy, especially when standing up quickly, due to the sedative effects of chlorpheniramine and the opioid nature of codeine.
• Constipation: Codeine can cause constipation, which is a common side effect of opioid medications.
• Nausea or Vomiting: Some people may experience gastrointestinal upset, particularly with codeine.

Serious side effects (though rare) include:

• Respiratory Depression: Due to codeine’s opioid properties, excessive use or high doses can depress breathing, which can be dangerous, especially in children or elderly individuals.
• Addiction or Misuse: Codeine is an opioid and has the potential for abuse and addiction, especially with prolonged use or higher-than-recommended doses.
• Severe Allergic Reactions: Rarely, some individuals may have an allergic reaction to either chlorpheniramine or codeine, including rash, swelling, or difficulty breathing. Seek medical attention if these symptoms occur.

If you experience any serious side effects, stop taking the medication and contact your doctor immediately.

Before using chlorpheniramine and codeine, you should take certain precautions:

• Pregnancy and Breastfeeding: This combination should only be used during pregnancy if absolutely necessary. Codeine passes into breast milk and may cause serious side effects in infants. Always consult your healthcare provider before using this medication if you are pregnant or breastfeeding.
• Liver or Kidney Disease: Codeine is metabolized in the liver, and reduced liver function can affect the way the drug works. If you have liver or kidney problems, your doctor may need to adjust the dosage.
• Alcohol Use: Alcohol can enhance the sedative effects of both chlorpheniramine and codeine, increasing the risk of serious side effects. Avoid consuming alcohol while using this medication.
• Children: Due to the risk of respiratory depression, codeine is generally not recommended for children under 12 years of age. It can cause serious or fatal breathing problems in young children.
• Driving and Operating Machinery: Because this medication causes drowsiness, avoid driving or operating machinery until you know how it affects you.

Chlorpheniramine and codeine can interact with several medications, including:

• Other central nervous system depressants: Combining with other sedatives, alcohol, or narcotic pain medications may increase the risk of excessive sedation, respiratory depression, and even overdose.
• Monoamine oxidase inhibitors (MAOIs): Using codeine with MAOIs can lead to severe reactions such as high blood pressure, seizures, or serotonin syndrome.
• Other antihistamines: If used with other antihistamines, the sedative effects may be intensified, leading to drowsiness and dizziness.

It is important to tell your doctor about all the medications, including over-the-counter drugs and herbal supplements, you are taking to avoid harmful interactions.

The typical adult dosage for Chlorpheniramine and Codeine is 1 teaspoon (5 mL) of syrup every 4-6 hours or 1 tablet every 4-6 hours, depending on the specific formulation. It is important not to exceed 60 mg of chlorpheniramine and 60 mg of codeine in a 24-hour period.

Always follow your doctor’s specific instructions regarding dosage and duration of treatment.

Chlorpheniramine and codeine is a prescription medication due to the presence of codeine, an opioid. It should only be used under the supervision of a healthcare provider to avoid misuse, overdose, or dependency. It is important to use this medication only as directed and not to share it with others.

1. What is Chlorpheniramine and Codeine used for?
   It’s used to treat cough and upper respiratory symptoms caused by allergies or the common cold.

2. How does Chlorpheniramine and Codeine work?
   Chlorpheniramine is an antihistamine that relieves allergy symptoms; Codeine is a narcotic cough suppressant.

3. Is this medication available over-the-counter?
   No, it is a prescription-only medication.

4. Can Chlorpheniramine and Codeine make you sleepy?
   Yes, both ingredients can cause drowsiness or sedation.

5. Is it safe to drive after taking Chlorpheniramine and Codeine?
   No, avoid driving or operating heavy machinery as it may impair alertness.

6. How often can I take Chlorpheniramine and Codeine?
   Usually every 4–6 hours as needed, but follow your doctor’s instructions.

7. Can I take this medication with alcohol?
   No, combining it with alcohol increases the risk of dangerous side effects.

8. What are the common side effects of Chlorpheniramine and Codeine?
   Drowsiness, dizziness, nausea, constipation, and dry mouth.

9. Can I give this medicine to children?
   It’s not recommended for children under 18 unless specifically prescribed.

10. Is this medication habit-forming?
    Yes, because Codeine is an opioid, it has the potential for addiction or abuse.

11. Can I take Chlorpheniramine and Codeine while pregnant?
    Consult a doctor; it is not usually recommended during pregnancy.

12. Does this medication interact with other drugs?
    Yes, especially CNS depressants, alcohol, and certain antidepressants.

13. How should I store this medication?
    Store at room temperature, away from moisture and light.

14. What should I do if I miss a dose?
    Take it as soon as you remember, but skip it if it’s almost time for the next dose.

15. What happens in case of an overdose?
    Seek emergency help immediately. Symptoms may include extreme drowsiness, confusion, or difficulty breathing.

16. Can I use it for a chronic cough?
    It’s generally intended for short-term use; consult your doctor for chronic symptoms.

17. What should I avoid while using this medication?
    Alcohol, sedatives, and driving should be avoided.

18. Is there a risk of withdrawal symptoms?
    Yes, especially if taken for a long time and then suddenly stopped.

19. How long does it take to start working?
    Usually within 30 to 60 minutes after taking the dose.

20. Can I crush or split the tablets?
    Follow your doctor’s advice—some formulations may be extended-release and should not be split.