Chlorpheniramine and pseudoephedrine

Common Brands Allerest, Chlor-Trimeton-D, Deconamine
Drug Class
Antihistamine and Decongestant combination
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Over-the-counter and prescription
Robert Chad Hakim, PharmD, BCCCP
Robert Chad Hakim, PharmD, BCCCP
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Medically reviewed by Robert Chad Hakim, PharmD, BCCCP last update on 20/12/2023

Overview

Chlorpheniramine and pseudoephedrine is a combination medication commonly used to treat symptoms of allergies, colds, and sinus congestion. It combines two active ingredients: chlorpheniramine, an antihistamine, and pseudoephedrine, a decongestant. Together, they help relieve common cold, flu, and allergy symptoms, such as sneezing, runny nose, nasal congestion, and sinus pressure.

  • Chlorpheniramine is an antihistamine that works by blocking histamine, a chemical released during allergic reactions. By doing so, it helps reduce symptoms like sneezing, itching, and a runny nose.
  • Pseudoephedrine is a decongestant that works by narrowing the blood vessels in the nasal passages, which reduces swelling and congestion, making it easier to breathe through the nose.

Together, chlorpheniramine and pseudoephedrine provide relief from multiple symptoms associated with allergies and upper respiratory infections.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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