Cibinqo is available in oral tablet form, and it is taken by mouth. It is important to follow your healthcare provider’s instructions carefully when taking this medication.
- Take the Medication Regularly: To get the best results, take Cibinqo regularly at the prescribed dose. Setting a routine can help you remember to take the medication each day.
- Avoid Skipping Doses: If you miss a dose, take it as soon as you remember, unless it is close to your next scheduled dose. Do not take two doses at once to make up for a missed dose.
- Avoid Crushing or Breaking the Tablets: Swallow the tablets whole with a glass of water. Do not crush or break them.
- Follow Dietary Instructions: Cibinqo can be taken with or without food, so there are no special dietary restrictions while using the medication.
Cibinqo works by inhibiting Janus kinases, which are enzymes that play a role in the inflammatory process. When these enzymes are active, they can trigger an overactive immune response, leading to inflammation and symptoms such as redness, swelling, and itching in the skin. By blocking these enzymes, Cibinqo helps to reduce inflammation, calm the skin, and relieve itching.
The medication works specifically by targeting JAK1, which is a key enzyme involved in the signaling pathways that lead to inflammation. By blocking this pathway, Cibinqo helps to regulate the immune response and reduce the symptoms of eczema.
It is important to note that Cibinqo is not a cure for eczema, but it can help manage the symptoms and improve the overall condition of the skin. It can provide relief for individuals who do not respond well to other treatments, such as topical steroids or moisturizers.
Like all medications, Cibinqo can cause side effects, although not everyone will experience them. Some of the common and less common side effects include:
- Common Side Effects:
- Headache: Some people may experience headaches while taking Cibinqo.
- Nausea: Stomach upset or nausea may occur, especially when first starting the medication.
- Upper Respiratory Infections: Cibinqo may increase the risk of infections, particularly upper respiratory infections, such as a cold or sinus infection.
- Diarrhea: Some people may experience digestive issues like diarrhea.
- Serious Side Effects:
- Increased Risk of Infection: Because Cibinqo suppresses certain aspects of the immune system, it can increase the risk of serious infections, including tuberculosis, bacterial infections, or fungal infections.
- Blood Clots: There is a potential increased risk of blood clots or cardiovascular events, so individuals with a history of these conditions should inform their doctor.
- Liver Issues: In rare cases, Cibinqo can affect liver function, so regular monitoring of liver enzymes is important during treatment.
If you experience any signs of infection, such as fever, cough, or sore throat, or notice any unusual side effects, contact your doctor right away.
There are several important warnings and precautions to keep in mind when using Cibinqo:
- Increased Risk of Infection: Since Cibinqo can weaken the immune system, it is important to avoid exposure to people with infections and to get vaccinated against preventable diseases before starting the medication.
- Liver and Kidney Health: If you have a history of liver or kidney disease, Cibinqo may not be suitable for you, or you may require closer monitoring. Your doctor may run tests to check your liver function before and during treatment.
- Pregnancy and Breastfeeding: Cibinqo is not recommended for use during pregnancy unless absolutely necessary, as it may harm the unborn child. It is also not known whether the medication passes into breast milk, so consult your doctor if you are pregnant or breastfeeding.
- Older Adults: Older adults may be at an increased risk of certain side effects, such as infections or blood clots, and may require more careful monitoring during treatment.
Cibinqo can interact with other medications, including immunosuppressants, other JAK inhibitors, or drugs that affect the immune system. For this reason, it is essential to inform your doctor about all other medications you are currently taking, including over-the-counter drugs, vitamins, and herbal supplements. Your healthcare provider may adjust your treatment plan or monitor you more closely for side effects.
Cibinqo is usually prescribed at a starting dose of 100 mg once daily. Depending on how well the patient responds to the medication and how well it is tolerated, the dose may be reduced to 50 mg once daily. The doctor will monitor the patient’s response to the medication and adjust the dose if necessary.
It is important not to exceed the prescribed dose, as this may increase the risk of serious side effects. Always follow the instructions provided by your healthcare provider.
Cibinqo is available only with a prescription. This means that you must consult with a healthcare provider before starting treatment. They will assess whether Cibinqo is appropriate for your specific condition and provide you with the correct dosage and usage instructions.