D-Phen 1000

Common Brands D-Phen 1000, Depen, Cuprimine
Drug Class
Chelating agent (D-Penicillamine)
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Prescription only
Robert Chad Hakim, PharmD, BCCCP
Robert Chad Hakim, PharmD, BCCCP
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Medically reviewed by Robert Chad Hakim, PharmD, BCCCP last update on 20/12/2023

Overview

D-Phen 1000 is a prescription medication used to manage phenylketonuria (PKU), a rare genetic disorder in which the body cannot break down an amino acid called phenylalanine. If phenylalanine builds up in the blood, it can cause brain damage and other health issues. D-Phen 1000 contains tetrahydrobiopterin (BH4), a cofactor that helps improve the body’s ability to process phenylalanine and reduce its levels in the blood.

This medication is typically used as part of a treatment plan for individuals with PKU, alongside dietary changes that limit phenylalanine intake. D-Phen 1000 helps to improve phenylalanine metabolism and reduce the risks of high blood phenylalanine levels.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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