Dexbrompheniramine and phenylephrine

Common Brands Various generic and brand formulations; sometimes part of multi-symptom cold/allergy products
Drug Class
Antihistamine (dexbrompheniramine) and nasal decongestant (phenylephrine) combination
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
OTC and prescription, depending on formulation
Allison Barnes, PharmD
Allison Barnes, PharmD
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Medically reviewed by Allison Barnes, PharmD last update on 20/12/2023

Overview

Dexbrompheniramine and phenylephrine are often used together in medications to treat the symptoms of allergic reactions, colds, and other respiratory conditions. Dexbrompheniramine is an antihistamine, while phenylephrine is a decongestant. This combination helps relieve common symptoms like nasal congestion, sneezing, runny nose, and itchy eyes caused by allergies or the common cold.

The combination of these two medications provides a dual effect: Dexbrompheniramine works by blocking histamine, reducing allergy symptoms, while phenylephrine helps to shrink swollen blood vessels in the nasal passages, leading to reduced nasal congestion and improved airflow.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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