One of the primary uses of Dexilant is the treatment of GERD, a chronic condition in which stomach acid flows back into the esophagus, causing symptoms such as heartburn, regurgitation, and chest pain.
Dexilant can provide relief from these symptoms and help prevent complications associated with long-term acid exposure to the esophagus, such as esophageal ulcers and Barrett’s esophagus.
Erosive Esophagitis
Erosive esophagitis is a condition characterized by inflammation and erosion of the esophagus lining due to frequent exposure to stomach acid. Dexilant is effective in healing and preventing the recurrence of erosive esophagitis.
Zollinger-Ellison Syndrome
Zollinger-Ellison syndrome is a rare condition in which the stomach produces excessive amounts of acid. Dexilant can be prescribed to manage this condition and alleviate symptoms, which may include severe stomach ulcers.
How does Dexilant Works?
The way Dexilant works is by reducing the production of stomach acid in the stomach. It does this by inhibiting the activity of proton pumps, which are tiny structures in the lining of the stomach that produce acid. Here’s how Dexilant works:
Inhibition of Proton Pumps
Proton pump inhibitors like Dexilant work by reducing the production of stomach acid. These cells contain proton pumps, which are enzymes responsible for pumping acid into the stomach. Dexilant inhibits these proton pumps.
Acid Reduction
By inhibiting the proton pumps, Dexilant effectively reduces the production of gastric acid in the stomach. This decrease in stomach acid levels helps relieve the symptoms associated with conditions like GERD, including heartburn, acid regurgitation, and irritation of the esophagus.
Healing of Esophageal Damage
In addition to reducing acid production, Dexilant can promote the healing of erosive esophagitis, a condition characterized by damage to the lining of the esophagus due to stomach acid. By reducing acid exposure to the esophagus, Dexilant allows the tissue to heal over time.
While Dexilant is generally well-tolerated, like any medication, it can cause side effects in some individuals. Common side effects may include:
Common Side Effects:
- Headache
- Diarrhea
- Abdominal pain
- Nausea
- Vomiting
- Flatulence (gas)
- Constipation
- Dry mouth
- Throat irritation
Less Common/Rare Side Effects:
- Dizziness
- Fatigue
- Joint pain
- Muscle pain
- Back pain
- Rash or itching
- Difficulty breathing or swallowing (potentially serious)
- Swelling of the face, lips, tongue, or throat (potentially serious)
- Unusual bruising or bleeding (potentially serious)
- Low magnesium levels in the blood, which may lead to symptoms like muscle spasms, irregular heartbeat, or seizures (rare but serious)
It’s important to note that these side effects are not experienced by everyone and may vary in intensity. If you experience severe or persistent side effects, it is crucial to consult your healthcare provider.
Before starting Dexilant or any medication, it is essential to be aware of potential warnings and precautions:
Allergies
Inform your healthcare provider if you have a known allergy to dexlansoprazole or any other PPIs.
Kidney Disease
Individuals with severe kidney disease should use Dexilant with caution, as it may require dosage adjustment or monitoring by a healthcare professional.
Clostridium difficile Infection
Prolonged use of PPIs like Dexilant may increase the risk of Clostridium difficile infection, which can cause severe diarrhea. Contact your healthcare provider if you experience persistent diarrhea while taking Dexilant.
Fractures
Long-term use of Dexilant has been associated with an increased risk of bone fractures, particularly in older adults. Discuss this risk with your healthcare provider and consider regular bone density monitoring if you require extended treatment.
Pregnancy and Breastfeeding
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of Dexilant with your healthcare provider. It is essential to make an informed decision about its use during these periods.
Dexilant can interact with several medications, potentially affecting their effectiveness or increasing the risk of side effects. Some of the notable interactions include:
Clopidogrel
Dexilant may reduce the effectiveness of clopidogrel, a medication used to prevent blood clots. Discuss alternative treatment options with your healthcare provider if you are taking both drugs.
Methotrexate
Dexilant can increase the levels of methotrexate in the body, potentially leading to toxic effects. Your healthcare provider may need to adjust your methotrexate dosage if you are prescribed Dexilant.
Warfarin
Combining Dexilant with warfarin, a blood thinner, can increase the risk of bleeding.
Antiretroviral Drugs
Some antiretroviral medications used to treat HIV may interact with Dexilant, potentially affecting their absorption. Consult with your healthcare provider to manage these interactions effectively.
The dosage of Dexilant can vary based on the condition being treated, the severity of symptoms, and individual patient factors. It is essential to follow your healthcare provider’s instructions carefully. Dexilant is available in both capsule and oral suspension forms.
Typical Dosages:
- For GERD: The typical starting dose is 60 mg once daily for up to 8 weeks. For maintenance therapy, the dose may be reduced to 30 mg once daily.
- For Erosive Esophagitis: The recommended dose is 60 mg once daily for up to 8 weeks.
- For Zollinger-Ellison Syndrome: The initial dose may vary but is often higher, with adjustments made based on individual response.
It’s crucial to take Dexilant as prescribed, and if you miss a dose, take it as soon as you remember.
Dexilant is available by prescription only and should be used under the guidance of a healthcare provider. To obtain a prescription, follow these guidelines:
Evaluation
Your healthcare provider will evaluate your condition and may perform diagnostic tests, such as endoscopy, to determine the underlying cause of your symptoms.
Prescription
If Dexilant is deemed appropriate for your condition, your healthcare provider will provide you with a prescription and instructions for its use.
Follow-Up
It is essential to follow up with your healthcare provider as scheduled to monitor your progress and address any concerns or side effects.
What is Dexilant typically used for?
Dexilant, or dexlansoprazole, is a medication often prescribed to alleviate conditions related to stomach acid, such as acid reflux and erosive esophagitis.
Who has the authority to prescribe Dexilant for GERD and erosive esophagitis?
Healthcare professionals such as gastroenterologists or primary care physicians can recommend Dexilant after a thorough evaluation of your symptoms and medical background.
Where is a safe place to acquire Dexilant?
Dexilant can be obtained securely from any registered pharmacy, provided you have a valid prescription. Credible online pharmacies are also a viable option.
Why do doctors recommend Dexilant for issues related to acid reflux?
Dexilant is suggested for acid reflux issues because it diminishes the production of acid in the stomach, thus alleviating symptoms like heartburn.
How does Dexilant function within the stomach?
Dexilant acts by inhibiting the proton pumps present in the stomach lining, which are responsible for producing acid, thereby decreasing the amount of stomach acid.
Could Dexilant lead to severe side effects?
While Dexilant is generally well-tolerated, it can cause side effects such as diarrhea, abdominal discomfort, nausea, and bloating. In rare cases, it may lead to serious kidney issues or vitamin B-12 deficiency. It’s crucial to consult your physician if you notice any unusual symptoms.
What other medicines can be used in place of Dexilant for treating GERD?
There are other proton pump inhibitors like omeprazole, lansoprazole, and pantoprazole that can serve as alternatives to Dexilant. Your healthcare provider can guide you in choosing the best option based on your condition.
Who should refrain from taking Dexilant?
Individuals with severe liver disease, osteoporosis, low magnesium levels in the blood, or those with an allergy to dexlansoprazole should avoid Dexilant. It’s important to discuss your medical history with your doctor before beginning any new medication.
In which healthcare settings is Dexilant most frequently prescribed?
Dexilant is often prescribed across various healthcare platforms, including hospitals, clinics, and gastroenterology practices, for managing conditions such as GERD and erosive esophagitis.
Why might Dexilant cause diarrhea in some individuals?
Dexilant can lead to diarrhea as it modifies the balance of gut bacteria due to its acid-reducing effect.
How can one deal with Dexilant’s side effects?
Any side effects from Dexilant can often be managed by modifying the dosage or timing of the medicine. It’s vital to report any side effects to your healthcare provider promptly.
Is there a possibility of Dexilant interacting negatively with other medicines?
Yes, Dexilant can interact with certain medicines, including warfarin, methotrexate, and specific HIV drugs. Always keep your healthcare provider informed about all the medications you’re currently taking.
What precautions should one take while using Dexilant?
When using Dexilant, watch out for symptoms of low magnesium levels such as muscle spasms and irregular heartbeat. Also, avoid combining it with alcohol as it may enhance the risk of stomach damage.
Which pharmaceutical company produces Dexilant?
Dexilant is a product of Takeda Pharmaceuticals.
Where can I report any adverse effects from Dexilant?
Unfavorable effects from Dexilant should be reported to your healthcare provider or directly to the FDA via their MedWatch program.
Why is Dexilant classified as a proton pump inhibitor?
Dexilant falls under the category of proton pump inhibitors because it inhibits the proton pumps in the stomach lining responsible for acid production.
What is the proper way to store Dexilant?
Dexilant should be stored at room temperature, away from direct light and moisture. Keep it out of reach from children.
Will Dexilant help manage my symptoms of acid reflux?
Dexilant is often effective in controlling symptoms of acid reflux, such as heartburn and regurgitation. However, its effectiveness may vary among individuals, making it crucial to discuss this with your healthcare provider.
What is the suggested dosage of Dexilant?
The suggested dosage of Dexilant can vary based on the condition being treated and the patient’s response to the medication. Always adhere to your healthcare provider’s guidance.
How much time does it take for Dexilant to show its effect?
The onset of Dexilant’s effects can differ, but many patients start observing an improvement in their symptoms within 1-2 weeks of starting the medication. The full therapeutic effects may take up to a month or more to appear. Always consult with your healthcare provider for precise information.