Dextromethorphan and phenylephrine

Common Brands Sudafed PE Cough & Cold, DayQuil Cough, various generics
Drug Class
Cough suppressant (Dextromethorphan) + Nasal decongestant (Phenylephrine)
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Over-the-counter
Kristianne Hannemann, PharmD
Kristianne Hannemann, PharmD
Read More
Medically reviewed by Kristianne Hannemann, PharmD last update on 20/12/2023

Overview

Dextromethorphan and phenylephrine are often found together in over-the-counter (OTC) medications aimed at treating symptoms associated with the common cold, flu, and other respiratory conditions. These medications provide relief from a combination of symptoms like cough, nasal congestion, and runny nose.

  • Dextromethorphan is a cough suppressant that works by affecting the signals in the brain that trigger the cough reflex, helping to control dry, persistent coughs.
  • Phenylephrine is a decongestant that works by narrowing the blood vessels in the nasal passages, leading to reduced swelling and congestion. This helps to open up blocked airways, making it easier to breathe.

Together, these two ingredients can offer a comprehensive solution for people dealing with both coughing and nasal congestion.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

Understanding Seborrheic Dermatitis: Causes, Symptoms, and Treatment

Seborrheic dermatitis is a widespread chronic inflammatory skin disorder that primarily affects the head, scalp, and upper trunk, which are areas rich in sebaceous glands. Despite not being a fatal illness, the chronic nature of the disorder and its frequent flare-ups can greatly lower the person’s standard of life. The goal of this thorough investigation

Read More »

Exploring the Connection Between Gut-Brain Axis

For a considerable time, both scientists and medical experts have been fascinated by the connection between the gastrointestinal tract and the brain. The gut-brain axis is a concept that has emerged from emerging research that highlights the deep relationship between both of these seemingly different organs. We will explore the elements, functions, and consequences associated

Read More »

A Comprehensive Overview of Food Intolerance

Food intolerances are becoming more widely acknowledged as serious health issues impacting people all over the world. In contrast to food allergies, which are immune system-related, food intolerances usually refer to the body’s incapacity to properly digest specific substances or dietary ingredients. This thorough review explores several kinds of food intolerances, such as fructose malabsorption,

Read More »