Dextromethorphan and pyrilamine

Common Brands Found in various multi-symptom nighttime cold products (generic and store brands)
Drug Class
Cough suppressant (Dextromethorphan) + Antihistamine (Pyrilamine)
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Over-the-counter
Allison Barnes, PharmD
Allison Barnes, PharmD
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Medically reviewed by Allison Barnes, PharmD last update on 20/12/2023

Overview

Dextromethorphan and pyrilamine are two common ingredients found in over-the-counter cold and allergy medications. These ingredients work together to relieve several symptoms that people experience when they have colds, allergies, or other respiratory issues.

  • Dextromethorphan is mainly a cough suppressant, used to reduce the urge to cough, especially when the cough is dry and non-productive. It works by affecting the cough center in the brain.
  • Pyrilamine is an antihistamine, used to reduce symptoms caused by allergies, such as runny nose, sneezing, and watery eyes. It works by blocking the effects of histamine, a substance that causes allergic reactions.

These two ingredients combined can provide effective relief from both coughing and allergy symptoms in people suffering from upper respiratory issues.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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