Using Fasenra Prefilled Syringe is easy, but you need to follow the correct procedure to make sure you are using it safely.

• Step 1: Wash your hands thoroughly.

   

• Step 2: Remove the syringe from the fridge. Let it warm to room temperature for at least 30 minutes before injecting.

   

• Step 3: Choose an injection site (thigh, abdomen, or upper arm). Clean the area with an alcohol wipe.

   

• Step 4: Remove the cap from the syringe and hold it like a pencil.

   

• Step 5: Gently insert the needle into the skin and inject the medicine slowly.

   

• Step 6: Once the injection is complete, dispose of the syringe safely in a sharps container.

   

It’s essential to rotate injection sites to prevent skin irritation or soreness.

Fasenra Prefilled Syringe works by targeting and reducing eosinophils in the body. These white blood cells cause inflammation, leading to asthma symptoms. By reducing the number of eosinophils, Fasenra helps to lower the inflammation in the airways, making it easier to breathe.

• Fasenra is a monoclonal antibody that attaches to eosinophils.

   

• It binds to the IL-5 receptor alpha on eosinophils and helps the body destroy them.

   

• Fewer eosinophils means less inflammation and fewer asthma attacks.

   

In simple terms, Fasenra Prefilled Syringe helps the immune system remove the cells causing asthma symptoms, leading to better control over asthma.

Like all medicines, Fasenra Prefilled Syringe can cause side effects. However, not everyone will experience them. Most side effects are mild and go away with time, but some can be serious.

Common side effects:

• Headache

   

• Sore throat

   

• Fever

   

• Injection site reactions (redness, pain, swelling, itching)

   

Serious side effects:

• Allergic reactions (rash, swelling, difficulty breathing)

   

• Infections (such as a cold or flu)

   

• Low white blood cell count

   

What to do:

• If you experience swelling, a rash, or difficulty breathing, get medical help immediately.

   

Report any side effects to your healthcare provider, especially if they are persistent or troublesome.

Fasenra Prefilled Syringe is a safe and effective treatment for many patients, but there are some important warnings and precautions to be aware of.

• Not for emergency use: Fasenra is not a treatment for sudden asthma attacks. Always have a fast-acting inhaler (rescue inhaler) with you.

   

• Tell your doctor if you have:

   

  • Parasitic infections

     

  • Allergic reactions to other biologic treatments

     

  • Immune system problems

     

  • A history of infections

     

• Pregnancy and breastfeeding: Fasenra should only be used during pregnancy if necessary. It’s not known if Fasenra is safe for breastfeeding, so consult your doctor before using it.

   

Vaccinations: Talk to your doctor before getting any vaccines while on Fasenra.

Fasenra Prefilled Syringe has few known interactions with other medications, but it’s important to inform your doctor about all the medications you are taking, including:

• Other asthma treatments

   

• Allergy medications

   

• Supplements

   

• Herbal products

   

This ensures there are no interactions that could affect the way Fasenra works.

Fasenra Prefilled Syringe comes with clear dosing guidelines. It’s important to stick to the schedule your doctor provides for maximum effectiveness.

• Initial dose: 30 mg every 4 weeks for the first 3 doses.

   

• Maintenance dose: After the first 3 doses, you’ll receive 30 mg every 8 weeks.

   

• Follow up with your doctor to monitor your asthma symptoms and adjust the treatment plan if needed.

   

What to remember:

• Do not skip doses, as regular treatment is essential for controlling asthma.

   

If you miss a dose, consult your doctor about the best time to take your next dose.

Fasenra Prefilled Syringe is available only with a doctor’s prescription. Your doctor will decide if this treatment is right for you based on your asthma history and symptoms.

• To get a prescription, you may need to undergo some tests to check your asthma severity and eosinophil levels.

   

• Your doctor will monitor your progress throughout the treatment, ensuring the medicine is working and adjusting your dose as needed.

   

Insurance and support:

• Fasenra Prefilled Syringe may be covered by insurance plans. Be sure to check with your insurance company for coverage details.

   

• There are patient assistance programs available for people who have trouble paying for the medicine.

   

• What is Fasenra Prefilled Syringe used for?
  It is prescribed to treat severe eosinophilic asthma in adults and children 12 years and older, helping reduce asthma attacks and the need for oral corticosteroids.

• What is the active ingredient?
  Benralizumab, a monoclonal antibody.

• How does Fasenra work?
  It targets and binds to interleukin-5 receptor alpha (IL-5Rα) on eosinophils, signaling the immune system to eliminate these inflammatory cells — reducing airway inflammation.

• What is the Fasenra Prefilled Syringe?
  It’s a single-use, prefilled syringe containing a fixed dose of benralizumab, designed for subcutaneous (under the skin) injection by a healthcare professional.

• How is Fasenra Prefilled Syringe administered?
  Injected under the skin of the upper arm, thigh, or abdomen — typically by a nurse or doctor in a clinic.

• What is the usual dosing schedule?

  • Once every 4 weeks for the first 3 doses, then

  • Once every 8 weeks thereafter (maintenance phase).

• Can patients self-inject with the prefilled syringe?
  The prefilled syringe is usually administered by a healthcare provider, though in some cases, trained patients may self-inject if approved.

• What are the common side effects?
  Headache, sore throat, fever, fatigue, and mild injection site reactions (pain, redness, itching).

• Are there serious side effects?
  Rare but possible — severe allergic reactions, rash, swelling, or anaphylaxis. Seek immediate help if symptoms occur.

• Is Fasenra Prefilled Syringe a steroid?
  No, it is a biologic (monoclonal antibody), not a corticosteroid.

• Does Fasenra replace inhalers?
  No — it is used alongside inhaled corticosteroids and other asthma medications.

• How should Fasenra Prefilled Syringe be stored?

  • Keep refrigerated (36°F–46°F / 2°C–8°C).

  • Protect from light; do not freeze.

  • It may be kept at room temperature (up to 77°F / 25°C) for up to 14 days before use.

• What should I do if I miss an injection?
  Contact your doctor to reschedule as soon as possible—do not double doses.

• How quickly does Fasenra work?
  Many patients notice improvement in symptoms within 4–8 weeks, but full benefit develops over several months.

• Who should not use Fasenra?
  People allergic to benralizumab or any ingredients in the formulation.

• Is it safe during pregnancy?
  Use only if clearly needed; discuss risks and benefits with your doctor.

• Can I use Fasenra while breastfeeding?
  Unknown if it passes into breast milk; consult your healthcare provider before use.

• Can I receive vaccines while on Fasenra?
  Most vaccines are safe, but live vaccines should be avoided unless approved by a doctor.

• Is there a generic available?
  No, Fasenra Prefilled Syringe (benralizumab) is currently brand only.

• Where can I get Fasenra Prefilled Syringe?
  Available at clinics, hospitals, or specialty pharmacies with a prescription.