How to Take Femhrt:

• Take 1 tablet daily, by mouth, at the same time each day.
  
  
• Swallow it with water, with or without food.
  
  
• Do not skip days, even if you feel better.
  
  

If you miss a dose:

• Take it as soon as you remember.
  
  
• If it’s almost time for the next dose, skip the missed dose—do not double up.
  
  

Your doctor may recommend regular follow-ups to check your response to treatment and adjust your dosage if needed.

During menopause, a woman’s body makes less estrogen and progesterone. These hormone changes can cause symptoms like:

• Hot flashes
  
  
• Sleep problems
  
  
• Mood swings
  
  
• Vaginal dryness
  
  
• Bone thinning
  
  

Femhrt works by replacing the hormones your body no longer makes. The estrogen helps reduce menopause symptoms, while the progestin helps protect the uterus from harmful changes that could lead to cancer.

Together, these hormones help restore balance and reduce discomfort caused by hormone loss.

Like all medicines, Femhrt can cause side effects. Some are mild and go away over time, while others may need medical attention.

Common side effects:

• Nausea
  
  
• Headache
  
  
• Breast tenderness
  
  
• Bloating
  
  
• Mood changes
  
  
• Weight changes
  
  
• Spotting or light bleeding between periods
  
  

Serious side effects:

• Blood clots (in the legs or lungs)
  
  
• Stroke
  
  
• Heart attack
  
  
• Liver problems (yellowing of skin or eyes)
  
  
• High blood pressure
  
  
• Breast lumps
  
  
• Vision problems
  
  

Call your doctor right away if you notice:

• Chest pain or trouble breathing
  
  
• Severe headache or dizziness
  
  
• Swelling or pain in your legs
  
  

Unusual vaginal bleeding

Femhrt may not be safe for all women. Talk to your doctor before starting it.

Do NOT use Femhrt if you:

• Have or had breast cancer
  
  
• Have liver disease
  
  
• Have a history of blood clots, stroke, or heart attack
  
  
• Are pregnant or think you might be
  
  
• Have undiagnosed vaginal bleeding
  
  
• Have had uterine or ovarian cancer
  
  

Use with caution if you:

• Have diabetes
  
  
• Have high blood pressure
  
  
• Have migraine headaches
  
  
• Have asthma or epilepsy
  
  
• Smoke cigarettes (especially over age 35)
  
  

Your doctor will check your medical history, blood pressure, and other health factors before prescribing Femhrt. You may also need yearly exams, including breast checks and pelvic exams.

Femhrt can interact with other medications, including:

• Antibiotics (like rifampin)
  
  
• Seizure medicines (like phenytoin, carbamazepine)
  
  
• HIV drugs
  
  
• Herbal products like St. John’s Wort
  
  
• Thyroid medications
  
  

These interactions can make Femhrt less effective or cause side effects. Always tell your doctor about all the medicines, supplements, and vitamins you take.

Femhrt comes in two strengths:

• 0.5 mg estrogen / 0.1 mg progestin
  
  
• 1 mg estrogen / 0.5 mg progestin
  
  

Your doctor will start you on the lowest dose possible to control your symptoms. You may need:

• A higher dose if symptoms continue
  
  
• A lower dose if you experience side effects
  
  

It’s important to take Femhrt exactly as directed, and not to stop suddenly unless your doctor says it’s safe.

Long-term use of hormone therapy should be reviewed every 6–12 months.

Femhrt is a prescription-only medicine, which means you need a doctor’s approval to use it.

Before prescribing Femhrt, your doctor will:

• Ask about your menopause symptoms
  
  
• Check for any medical conditions
  
  
• Review your family history (especially of cancer, heart disease, or blood clots)
  
  
• Order lab tests or scans if needed (like a bone density test)
  
  

Because Femhrt contains hormones, regular check-ups are important to monitor your health and response to treatment.

• What is Femhrt used for?
  It is a hormone replacement therapy (HRT) used to:

  • Treat moderate to severe hot flashes and night sweats caused by menopause

  • Help prevent postmenopausal osteoporosis in women at high risk

• What are the active ingredients?

  • Ethinyl estradiol (estrogen)

  • Norethindrone acetate (progestin)

• How does Femhrt work?

  • Estrogen replaces the natural estrogen your body no longer produces after menopause.

  • Progestin helps protect the uterus from overgrowth of the lining (endometrial hyperplasia) that can occur with estrogen alone.

• What forms and strengths are available?

  • Femhrt 0.5 mg/2.5 mcg tablets

  • Femhrt 1 mg/5 mcg tablets
    Both are taken orally once daily.

• How should Femhrt be taken?
  Take one tablet daily, at the same time each day, with or without food.

• Can Femhrt be used after hysterectomy?
  Usually not needed, since women without a uterus can take estrogen alone (without progestin).

• What are the common side effects?
  Nausea, headache, breast tenderness, bloating, vaginal spotting, mood changes, or mild leg cramps.

• Are there serious side effects?
  Yes — Femhrt carries boxed warnings for:

  • Increased risk of blood clots, stroke, and heart attack

  • Increased risk of breast cancer with long-term use

  • Dementia risk in women aged 65 and older taking combined HRT

• Who should not take Femhrt?

  • Women with a history of breast or uterine cancer

  • Those with blood clots, stroke, or liver disease

  • Women who are pregnant or suspect pregnancy

  • Those with undiagnosed abnormal vaginal bleeding

• Can Femhrt be used for osteoporosis prevention?
  Yes — it helps slow bone loss, but is generally reserved for women who cannot tolerate other osteoporosis medications.

• Does Femhrt affect menstruation?
  Some women may experience light bleeding or spotting during the first few months of therapy.

• Can Femhrt help with vaginal dryness?
  It may help slightly, but local vaginal estrogen creams or tablets are more effective for dryness alone.

• How long should Femhrt be taken?
  Use the lowest effective dose for the shortest possible duration, with annual reevaluation by your doctor.

• Can I take Femhrt if I smoke?
  Smoking increases the risk of heart and clotting problems — strongly discouraged while using Femhrt.

• Can Femhrt cause weight changes?
  Mild fluid retention or bloating may occur, but significant weight gain is uncommon.

• Does Femhrt interact with other medications?
  Yes — it can interact with:

  • Rifampin

  • Carbamazepine

  • Phenytoin

  • St. John’s wort
    These can reduce Femhrt’s effectiveness by speeding hormone metabolism.

• Can Femhrt be used during pregnancy?
  No — Femhrt is contraindicated in pregnancy.

• Can I take Femhrt while breastfeeding?
  Not recommended — it may reduce milk production and small amounts can pass into breast milk.

• Do I need regular checkups while on Femhrt?
  Yes — regular mammograms, pelvic exams, and blood pressure checks are essential.

• Is there a generic version available?
  Yes — ethinyl estradiol and norethindrone acetate tablets are available as generics.

• Where can I get Femhrt?
  Available by prescription only from pharmacies.