| Common Brands | Nalfon, Nalfon 200 |
|---|---|
|
Drug Class |
Nonsteroidal Anti-Inflammatory Drug (NSAID) |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Prescription only |
Fenoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to reduce pain, inflammation, and fever. It is commonly prescribed for conditions such as arthritis, musculoskeletal pain, and dysmenorrhea (painful menstruation). Fenoprofen works by blocking the production of prostaglandins, substances in the body that cause inflammation, pain, and fever.
Fenoprofen is available in oral form, often as tablets or capsules, and is typically used for short-term management of pain or inflammation. Like other NSAIDs, Fenoprofen is an effective pain reliever, but it must be used with caution because it can have side effects, particularly when used long-term or in high doses.
While Fenoprofen is effective for managing pain, it should be used under medical supervision, especially for people with underlying health conditions such as kidney disease, gastrointestinal issues, or cardiovascular problems.
Fenoprofen is taken orally, usually with a full glass of water. Here’s how you should take Fenoprofen:
Missed dose: If you miss a dose, take it as soon as you remember, unless it’s almost time for your next dose. In this case, skip the missed
Fenoprofen works by inhibiting the action of two enzymes called cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2). These enzymes are involved in the production of prostaglandins, which are chemicals in the body that promote inflammation, pain, and fever.
By inhibiting these enzymes, Fenoprofen reduces pain and inflammation, making it particularly useful for conditions like rheumatoid arthritis, osteoarthritis, musculoskeletal injuries, and dysmenorrhea.
Like all medications, Fenoprofen can cause side effects. While many people tolerate it well, some may experience unwanted effects. The risk of side effects increases when Fenoprofen is taken for long periods or in high doses.
Though rare, Fenoprofen can cause serious side effects, especially when used long-term or in high doses. These may include:
Allergic reactions: In rare cases, Fenoprofen may trigger an allergic reaction, leading to symptoms such as rash, itching, swelling, or difficulty breathing. Seek immediate medical attention if you experience any signs of an allergic reaction.
Fenoprofen should be used with caution in certain populations. Before starting Fenoprofen, make sure your healthcare provider is aware of any existing medical conditions.
Fenoprofen can interact with a variety of other medications, potentially altering its effectiveness or increasing the risk of adverse effects. Some key drug interactions include:
Patients should always inform their healthcare provider about any other medications they are taking before starting Fenoprofen, including over-the-counter drugs and herbal supplements.
Fenoprofen should be taken exactly as prescribed by your doctor. The typical dosage varies based on the condition being treated. The following are general guidelines for adult patients:
Always follow your doctor’s specific dosage recommendations and do not exceed the prescribed amount.
Fenoprofen is a prescription medication, so it must be prescribed by a doctor. Your doctor will assess your medical condition and decide whether Fenoprofen is appropriate for you. Be sure to provide a full medical history, including any kidney, liver, heart, or gastrointestinal issues, as these conditions may affect your ability to use Fenoprofen safely.
What is Fenoprofen used for?
It is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve:
Pain and inflammation from arthritis (rheumatoid arthritis, osteoarthritis)
Mild to moderate pain from injuries, dental pain, or menstrual cramps
What are the brand names?
Nalfon®, Nalfon 200®, and generic Fenoprofen calcium.
What type of medication is Fenoprofen?
It is an NSAID — a medication that reduces pain, inflammation, and fever.
How does Fenoprofen work?
It blocks the enzymes COX-1 and COX-2 (cyclooxygenases), reducing production of prostaglandins, chemicals that cause pain, fever, and inflammation.
How is Fenoprofen taken?
Orally, as a capsule or tablet, usually every 6–8 hours with food or milk to minimize stomach upset.
What are the available strengths?
200 mg and 400 mg capsules are most common.
How long does it take to work?
Pain relief generally starts within 30–60 minutes after ingestion.
What are the common side effects?
Nausea, heartburn, indigestion, constipation, dizziness, or headache.
Are there serious side effects?
Yes — Fenoprofen carries boxed warnings for:
Increased risk of heart attack or stroke, especially with long-term use
Serious gastrointestinal (GI) bleeding, ulcers, or perforation, which may occur without warning
Other serious effects may include liver or kidney problems, or allergic reactions (rash, swelling, difficulty breathing).
Who should not take Fenoprofen?
Those with NSAID allergies (including aspirin sensitivity)
Patients with stomach ulcers, GI bleeding, or inflammatory bowel disease
Individuals with severe heart, liver, or kidney disease
People who have recently had heart bypass surgery (CABG)
Can Fenoprofen be used long-term?
Yes, but under close medical supervision, due to risks of heart and stomach complications.
Does Fenoprofen cause drowsiness?
Occasionally, yes — dizziness or mild drowsiness can occur. Avoid driving until you know how it affects you.
Can I drink alcohol while taking Fenoprofen?
Avoid alcohol — it increases the risk of stomach bleeding and liver strain.
Does Fenoprofen affect the kidneys?
Yes — long-term use may reduce kidney function, especially in dehydrated patients or those with preexisting kidney disease.
Can I take Fenoprofen during pregnancy?
Avoid during the third trimester — it can harm the baby’s heart or kidneys.
Use in early pregnancy only if prescribed by your doctor.
Can I take Fenoprofen while breastfeeding?
Small amounts may pass into breast milk — consult your doctor before use.
Can Fenoprofen be used with other pain relievers?
Avoid using with other NSAIDs (ibuprofen, naproxen).
It can be used with acetaminophen (Tylenol) if extra pain relief is needed.
Does Fenoprofen interact with other medications?
Yes — key interactions include:
Blood thinners (warfarin, apixaban) → increased bleeding risk
Corticosteroids → higher risk of GI ulcers
ACE inhibitors, ARBs, and diuretics → may reduce kidney function
SSRIs/SNRIs → increased bleeding risk
What should I do if I miss a dose?
Take it as soon as you remember unless it’s almost time for your next dose — don’t double up.
How should I store Fenoprofen?
Store at room temperature (20°C–25°C / 68°F–77°F), away from moisture and heat.
Is there a generic available?
Yes — Fenoprofen calcium is available as a generic medication.
Where can I get Fenoprofen?
Available by prescription only at pharmacies.
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