| Common Brands | FIRST-Testosterone |
|---|---|
|
Drug Class |
Testosterone (Topical) |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Prescription only |
FIRST-Testosterone is a prescription medicine that contains testosterone, the main male sex hormone. It is used to treat men who have low levels of testosterone in their body, a condition known as hypogonadism.
This medicine helps by replacing the missing hormone and bringing testosterone levels back to normal. It can help improve symptoms like:
FIRST-Testosterone usually comes as a topical ointment or cream, applied directly to the skin. It is used only under a doctor’s guidance.
FIRST-Testosterone should be used exactly as your doctor tells you. It is for external use only—do not swallow or inject it.
Avoid skin contact with others, especially women and children, until the area is washed or covered with clothing.
Testosterone is a hormone made in the testicles in men. It is important for:
Some men have low testosterone due to age, injury, or health problems. FIRST-Testosterone gives the body extra testosterone to replace what it is missing.
The hormone is absorbed through the skin into the bloodstream, helping the body function normally again.
FIRST-Testosterone may cause some side effects, but not everyone gets them. Most are mild and manageable, especially if used correctly.
Call your doctor right away if you notice chest pain, leg pain, or vision changes.
Before using FIRST-Testosterone, tell your doctor if you have:
Your doctor will check your blood testosterone levels, PSA, and liver function regularly.
Testosterone can interact with other medicines. Tell your doctor if you use:
These interactions can cause serious side effects, so your doctor may need to monitor your treatment closely.
The doctor will decide the best dose for you based on:
If you miss a dose, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed one—do not use double the amount.
Do not stop using the medicine suddenly without your doctor’s advice.
FIRST-Testosterone is a controlled substance, which means:
Doctors will monitor your treatment to make sure it is safe and effective. Misusing testosterone can be dangerous, especially in bodybuilding or sports.
Never share your testosterone with others. Store the medicine safely and out of reach of children.
What is FIRST-Testosterone used for?
It is used to treat low testosterone (hypogonadism) in adult men by restoring normal hormone levels, improving energy, libido, muscle mass, and mood.
What is the brand name?
FIRST-Testosterone® (by CutisPharma).
What is the active ingredient?
Testosterone USP — a bioidentical androgen hormone identical to the testosterone produced naturally in the body.
How does FIRST-Testosterone work?
Replaces or supplements testosterone in men with low levels.
Helps maintain muscle strength, bone density, red blood cell production, and sexual function.
What type of medication is it?
A topical testosterone replacement therapy (TRT).
How is FIRST-Testosterone applied?
Applied to the skin (topically), usually on shoulders, upper arms, or abdomen, once daily.
Wash hands thoroughly after application.
Allow the gel to dry completely before dressing or skin contact with others.
What are the available forms and strengths?
FIRST-Testosterone Cream 2% (20 mg/g)
FIRST-Testosterone MC Cream 1% (10 mg/g)
Supplied as ready-to-use unit-dose packets or metered pumps.
How long does it take to work?
Energy and mood improvements may occur within 2–4 weeks.
Full benefits (muscle mass, sexual function, bone density) may take 3–6 months.
What are the common side effects?
Skin irritation or redness at the application site
Acne or oily skin
Hair growth on treated areas
Increased red blood cell count (polycythemia)
Mild mood changes or irritability
Are there serious side effects?
Rare but serious:
Blood clots or deep vein thrombosis (DVT)
Heart attack or stroke risk increase
Prostate growth or cancer progression
Liver abnormalities (rare with topical forms)
Sleep apnea worsening
Who should not use FIRST-Testosterone?
Men with prostate or breast cancer
Those with untreated severe heart, kidney, or liver disease
Women or children — accidental exposure can cause virilization (hair growth, deepened voice, etc.)
Can it be used during pregnancy?
No — teratogenic (can harm the fetus). Pregnant women should avoid contact with treated skin areas.
Can it be used while breastfeeding?
No — exposure risk to infants.
Does FIRST-Testosterone interact with other medications?
Anticoagulants (warfarin) – may increase bleeding risk.
Insulin or diabetes medications – testosterone can lower blood glucose.
Corticosteroids – may increase fluid retention.
How should I store FIRST-Testosterone?
Store at room temperature (20 °C–25 °C / 68 °F–77 °F).
Keep tightly closed and away from heat or flame.
Do not refrigerate or freeze.
Is there a generic available?
Testosterone creams and gels are available generically, but FIRST-Testosterone® is a brand-compounded pharmacy product.
Where can I get it?
Available by prescription only, dispensed through compounding or specialty pharmacies.
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