Atelvia consists of sodium risendronate which is a member of a group of drugs called bisphosphonates and it’s mode of action is inhibition of cells called osteoclast responsible for uptaking and resorbing bone.
Osteoclast-associated bone loss would be inhibited and thus retained bone density and/or gain in bone mass if osteoclast activity would be inhibited or turned off for a certain time. In terms of improving the healing process, this will result in an increase in bone-mineral density thereby making the bones less susceptible to fractures.
The delayed-release formula of Atelvia allows absorption of the drug in the intestine rather than the stomach where there is little or no abrasive effect on the drug or the walls of the esophagus. Since this is a controlled release formulation, the incidence of gastrointestinal adverse effects associated with such medications is usually lower than that seen with other bisphosphonates like alendronate.
As is the case with all the medications in the market, Atelvia has some side effects too, which, however, may be experienced by some individuals. Among the prevalent side effects related to Atelvia, we have the following:
- A fixed sentence template for providing a particular syntactic form – only sustainable development can help achieve this. In addition to that, some gastrointestinal complaints such as nausea, abdominal pain, dyspepsia (indigestion), or constipation may also prevail. Though such effects may tend to arise due to the prolonged action of the Atelvia’s active substance, preventative strategies are already built into the design.
- Pain in the muscular system: Pain in muscles, joints or bones is observed in a number of patients treated With Atelvia.
- Headache: Another such common side effect is headache with use of Atelvia.
- Antacids, Calcium Supplements, and Iron Supplements: Atelvia, a bisphosphonate used for treating osteoporosis, should not be taken with antacids, calcium, or iron supplements at the same time. These can interfere with the absorption of the medication, making it less effective. It is advised to take Atelvia at least 30 minutes before any of these products.
- Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Combining Atelvia with NSAIDs (such as ibuprofen or naproxen) may increase the risk of gastrointestinal irritation, ulcers, or bleeding. Both types of drugs can irritate the stomach, so it’s important to monitor for any stomach-related side effects.
- Aspirin: Similar to NSAIDs, aspirin can increase the risk of stomach problems when used with Atelvia, as both drugs can irritate the stomach lining. Caution is advised when taking these together.
- Other Bisphosphonates: Combining Atelvia with other bisphosphonates (used for bone health) can increase the risk of side effects like jaw bone problems (osteonecrosis) or esophageal irritation. Only one bisphosphonate should be taken at a time.
Always consult with a healthcare provider to avoid potential drug interactions and ensure safe use of Atelvia.
The standard recommended dosage of Atelvia is 35 mg per week, which is equivalent to one tablet. Patients are advised to ingest the tablet with a full glass of water on an empty stomach, which must be at least 30 minutes prior to food or beverage intake.
Special Considerations
- Patients with renal impairment should have their dosage adjustment monitored and controlled by their healthcare physicians as per their renal activity.
• Lost doses: Take your doctor’s advice whether to take the lost dose or wait until the next dosage cycle.
Atelvia is a prescription medicine available only with a doctor’s prescription. This medicine can be taken only under medical supervision. A doctor will examine your general health, bone density, and other risk factors for osteoporosis before he/she prescribes Atelvia. Because frequently it has to be controlled whether the drug brings the desired results without side effects (for example, bone densitometry, blood tests), several visits to the doctor may be required during the treatment.