| Common Brands | Breo Ellipta |
|---|---|
|
Drug Class |
ICS / LABA combo |
|
Controlled Substance Classification |
Not a controlled medication |
|
Generic Status |
Lower-cost generic available |
|
Availability |
Prescription only |
Breo Ellipta is prescribed for the management of chronic obstructive pulmonary diseases, including both asthma and COPD. It contains two active agents: fluticasone furoate, which is a corticosteroid, and vilanterol, which is a LABA. The effect of this medication is twofold-it reduces inflammation in the airways and relieves tension in the airway walls, thereby relaxing the muscles. This results in improved airflow and helps to reduce the symptoms of wheezing, breathlessness, and coughing.
Breo Ellipta is a long-term maintenance medication, not used for the immediate relief of acute asthma or COPD symptoms but rather for maintaining control over these conditions. It comes in a dry powder inhaler (Ellipta device) and is prescribed to patients with moderate to severe asthma or COPD for the prevention of flare-ups and improvement in breathing.
Breo Ellipta is administered using a dry powder inhaler device called Ellipta. Here are the general steps to use it:
Prepare the Inhaler:
Open the device by sliding the cover down until it clicks.
This will expose the inhaler’s mouthpiece and load a dose of the medication automatically.
You should hear a click, which indicates that the inhaler is ready for use.
Exhale:
Before using the inhaler, breathe out fully, away from the inhaler, to ensure your lungs are empty.
Inhale:
Place the mouthpiece to your lips, seal your lips around it, and inhale deeply and forcefully. Try to inhale as quickly and deeply as possible to ensure that the medication is delivered into your lungs.
Hold Your Breath:
After inhaling, hold your breath for about 10 seconds (or as long as comfortable) to allow the medication to settle in the lungs.
Exhale Slowly:
Exhale slowly and gently away from the inhaler.
Close the Inhaler:
Now slide the cover back over the mouthpiece of the inhaler to shut it.
Rinse Your Mouth:
It would be good to rinse the mouth with water and spout it out after using the Breo Ellipta to prevent potential side effects such as sore throat and infections through the fungi in the mouth.
Breo Ellipta combines the two active drugs to exert the following effect:
Fluticasone furoate (Corticosteroid): Fluticasone furoate is an inhaled corticosteroid (ICS) that reduces inflammation in the airways by inhibiting various inflammatory cells and mediators. These include eosinophils, mast cells, and cytokines that contribute to airway inflammation. Controlling inflammation prevents swelling and mucus buildup, which can narrow the airways and cause breathing difficulties.
Vilanterol (LABA): It is a long-acting beta-agonist that binds to the beta-2 adrenergic receptors on the smooth muscles of the airways, allowing smooth muscles of airways to relax and its calibre to increase, causing better airflow and reduction of symptoms such as wheeze and breathlessness. Therefore, keeping the airways open from time to time for up to 24 hours, a condition referred to as long term reliever.
Like all medications, Breo Ellipta may cause side effects, although not everyone experiences them. Common side effects include:
Throat Irritation: A sore or irritated throat is one of the frequently reported side effects of inhaled corticosteroids, such as fluticasone.
Coughing: A few patients might also cough following inhaler use.
Headache: Headache is a common side effect of most inhaled medications.
Oral Fungal Infections (Thrush): Because Breo Ellipta contains a corticosteroid, it may predispose to the development of oral candidiasis. This is why rinsing the mouth after use is recommended.
Hoarseness or Voice Changes: Some people may experience changes in their voice or hoarseness as a result of using the inhaler.
Increased Heart Rate: Because vilanterol belongs to the beta-agonist group, it may cause an increased heart rate in some subjects.
Not for Acute Symptoms: Breo Ellipta is not indicated for relief of acute bronchospasm. Patients should have a rescue inhaler such as albuterol available for acute asthma or COPD attacks.
The inhaled corticosteroids prolong exposure to which may sometimes cause side effects like oral fungal infections, cataracts, and osteoporosis. Dosage should be strictly followed. Do not overuse.
Heart Diseases: Patients with heart disease or hypertension should use the drug cautiously because beta-agonists like vilanterol will influence heart rate as well as blood pressure.
Risk of Infections: The use of corticosteroids may make one more susceptible to infections. Patients on Breo Ellipta should also avoid exposure to other persons who have infections, especially fungal infections.
Not for Children Under 18: Breo Ellipta is not approved for use in pediatric patients under 18 years of age.
Always consult with a healthcare provider to ensure safe use when combining medications with Breo Ellipta.
For COPD: Adults 1 inhalation (100 mcg fluticasone furoate / 25 mcg vilanterol) once daily.
For Asthma: The recommended dose for asthma is 1 inhalation (200 mcg fluticasone furoate / 25 mcg vilanterol) once daily.
The inhaler is designed to deliver one dose per day, and patients should use it consistently at the same time every day for maximum effectiveness.
Bre Ellipta is a prescription drug, which requires a doctor’s prescription. The doctor will check your symptoms, medical history, and the degree of your breathing problem before he recommends Breo Ellipta. Use Breo Ellipta exactly as directed by your doctor and never exceed the dose recommended.
Breo Ellipta is a prescription inhalation medication that combines two active ingredients: fluticasone furoate (a corticosteroid) and vilanterol (a long-acting beta-agonist). It is used to help control asthma and COPD symptoms.
Breo Ellipta works by reducing inflammation in the lungs and relaxing the muscles around the airways, making it easier to breathe and decreasing nighttime symptoms.
Breo Ellipta is prescribed for adults and children aged 18 years and older who have asthma or COPD and need a long-term control medication to manage their symptoms.
Breo Ellipta is delivered via a dry powder inhaler. Users inhale a dose directly from the device, usually once daily, at the same time each day for optimal effectiveness.
The standard dosage is one inhalation once daily. It is important not to exceed the recommended dose.
Common side effects may include headache, throat irritation, hoarseness, cough, and upper respiratory tract infections. If side effects persist or worsen, contact your healthcare provider.
Yes, serious side effects can occur, including allergic reactions, chest pain, worsening shortness of breath, or increased heart rate. Seek immediate medical attention if these occur.
Pregnant or breastfeeding women should consult their healthcare provider before using Breo Ellipta. While it may be prescribed if benefits outweigh risks, caution is advised.
No, Breo Ellipta is not a rescue inhaler. It is meant for long-term control and management of asthma or COPD symptoms, not for sudden attacks. A separate rescue inhaler should be used for immediate relief.
Do not stop or reduce your dosage of Breo Ellipta without consulting your doctor, as abrupt discontinuation may worsen your symptoms.
If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Store Breo Ellipta at room temperature, away from moisture and heat. Keep it out of reach of children, and do not use it after the expiration date on the package.
Yes, certain medications, especially other inhaled corticosteroids or beta-agonists, can interact with Breo Ellipta. Always inform your healthcare provider about all medications you are taking.
Many patients may begin to notice improvements in symptoms within 24 hours of the first dose, but optimal control may take several days to a few weeks.
Patients with certain heart conditions, such as arrhythmias, may need to be cautious when using Breo Ellipta. Discuss your medical history with a healthcare provider for personalized advice.
Yes, Breo Ellipta can often be used alongside other asthma medications, but you should discuss any new or existing treatments with your healthcare provider for safe coordination.
Throat irritation and oral thrush are potential side effects of inhaled steroids. Rinse your mouth with water and spit after using the inhaler to reduce the risk. If symptoms persist, consult your doctor.
Breo Ellipta delivers a combination of corticosteroid and long-acting beta-agonist in a single inhaler, providing both anti-inflammatory and bronchodilator effects, which may be different from other inhalers that contain just one type of medication or a different formulation.
Yes, maintaining a healthy lifestyle, avoiding smoking, and managing allergens and irritants can significantly improve the effectiveness of Breo Ellipta and overall lung health.
For more information, refer to the patient information leaflet included with your medication, consult your healthcare provider, or visit reputable health websites like the FDA or the American Lung Association.
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