Ciclesonide is available in the form of an inhaler (Alvesco), which delivers the medication directly to the lungs. Here’s how to use the inhaler properly:
- Prepare the Inhaler: Remove the inhaler cap and shake it well to ensure the medication is mixed properly.
- Exhale Fully: Before using the inhaler, exhale fully to empty your lungs. This will make room for the medication when you inhale.
- Inhale the Medication: Place the mouthpiece in your mouth, close your lips around it, and inhale deeply and slowly through your mouth. Make sure not to breathe through your nose.
- Hold Your Breath: After inhaling the medication, hold your breath for about 10 seconds (or as long as is comfortable) to allow the medication to settle in the lungs.
- Repeat if Necessary: If your doctor has prescribed more than one inhalation, repeat the process as needed.
- Clean the Inhaler: After use, clean the inhaler according to the instructions to keep it working properly and avoid medication buildup.
It’s important to use the inhaler regularly as prescribed, even if you feel fine. Ciclesonide helps manage the condition over time, but it is not effective immediately during an asthma attack.
Ciclesonide works by targeting the underlying inflammation that occurs in the airways of the lungs in people with asthma and COPD. These conditions cause the airways to become swollen and narrow, making it difficult for air to flow freely. Inflammation is a key factor in these diseases, and ciclesonide helps to reduce this inflammation.
Once inhaled, ciclesonide is converted into its active form (des-ciclesonide) in the lungs. This active form then binds to specific receptors in the airway cells, reducing the production of substances that cause inflammation. By doing so, it helps to decrease swelling, mucus production, and airway constriction, improving airflow and making it easier to breathe.
While ciclesonide is generally well-tolerated, some people may experience side effects. The most common side effects include:
- Mouth Irritation: Some people may experience irritation or dryness in the mouth or throat after using the inhaler.
- Hoarseness or Voice Changes: The medication can cause hoarseness or changes in the voice in some individuals, particularly with long-term use.
- Coughing: Inhaled medications, including ciclesonide, can sometimes cause coughing or throat irritation after use.
- Fungal Infections: Using an inhaled corticosteroid like ciclesonide may increase the risk of fungal infections in the mouth or throat (e.g., thrush). Rinsing the mouth after each use can help reduce this risk.
- Headache: Some users may experience headaches as a side effect of the medication.
- Nasal Congestion: Nasal congestion or sinus issues may occur in some individuals.
- Increased Risk of Pneumonia (COPD patients): In people with COPD, there may be an increased risk of pneumonia. It is important to monitor for symptoms such as cough, fever, or chest discomfort.
In rare cases, people may experience more serious side effects, such as:
- Severe allergic reactions: Rash, itching, difficulty breathing, or swelling of the face or throat.
- Adrenal Suppression: Long-term use of inhaled corticosteroids can sometimes affect the adrenal glands, which produce essential hormones. This is more likely with high doses over a long period.
If you experience any severe side effects or signs of infection, contact your doctor immediately.
Before using ciclesonide, there are several important precautions to consider:
- Allergies: If you are allergic to ciclesonide or any of the ingredients in the inhaler, do not use it. Inform your doctor of any known allergies before starting the medication.
- Active Infections: If you have an active infection (especially a respiratory infection), talk to your doctor before using ciclesonide, as the medication can suppress the immune response and make it harder to fight off infections.
- Eye Problems: Inhaled corticosteroids, including ciclesonide, may increase the risk of cataracts or glaucoma with long-term use. Regular eye exams are recommended for people using corticosteroids over a long period.
- Pregnancy and Breastfeeding: Ciclesonide should be used during pregnancy only if the potential benefits outweigh the risks. It is also important to discuss breastfeeding with your doctor, as small amounts of the medication may pass into breast milk.
- Children: Ciclesonide is safe for children aged 4 years and older, but the dosage should be carefully monitored by a healthcare provider. Children may be more sensitive to corticosteroids, so they should be regularly monitored for side effects.
- Monitor for Side Effects: Regular visits to your doctor are important to monitor for any side effects or complications from long-term use of ciclesonide.
Ciclesonide may interact with other medications, particularly those that affect the metabolism of corticosteroids. Some medications, such as certain antifungal drugs (e.g., ketoconazole) and HIV medications (e.g., ritonavir), can increase the levels of ciclesonide in the body, raising the risk of side effects. It’s important to inform your healthcare provider about all other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements.
The usual recommended dosage of ciclesonide for adults and children over 12 years old with asthma is 80–160 mcg once or twice daily. For COPD, the typical dose is 160 mcg once a day. It is essential to follow the prescribed dose and never exceed the recommended amount.
Your healthcare provider will adjust the dosage based on your individual needs and response to the medication.
Ciclesonide is available only with a prescription from a healthcare provider. It is important to have a proper diagnosis and treatment plan for asthma or COPD before starting this medication. Always follow the instructions provided by your doctor and healthcare provider.