Dextromethorphan and pseudoephedrine

Common Brands Sudafed Cough, various generics
Drug Class
Cough suppressant (Dextromethorphan) + Nasal decongestant (Pseudoephedrine)
Controlled Substance Classification
Not a controlled medication
Generic Status
Lower-cost generic available
Availability
Over-the-counter (behind pharmacy counter in many regions)
Shifali Patel, PharmD
Shifali Patel, PharmD
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Medically reviewed by Shifali Patel, PharmD last update on 20/12/2023

Overview

Dextromethorphan and pseudoephedrine are two medications commonly used together to treat symptoms of colds, flu, and other respiratory conditions. Each medication works in a different way to help alleviate discomfort caused by common illnesses.

  • Dextromethorphan is primarily used as a cough suppressant. It works by acting on the brain to reduce the urge to cough, providing relief from dry, non-productive coughs that don’t produce mucus.
  • Pseudoephedrine is a decongestant. It works by narrowing the blood vessels in the nasal passages, which helps to reduce swelling and congestion, making it easier to breathe.

When used together, these two ingredients can provide relief from a variety of symptoms, including cough and nasal congestion, helping to improve overall comfort during an illness.

DRUG STATUS

Availability

Prescription only

Pregnancy & Lactation

Pregnancy

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