Dyanavel XR is taken once daily, usually in the morning. Because it is in liquid form, it can be administered easily to both children and adults.

• Shake Well Before Use: Since Dyanavel XR is a liquid, you need to shake the bottle well to ensure the medication is properly mixed before each dose.
  
  
• Measuring the Dose: The medication comes with a dosing syringe or cup. Be sure to measure the dose carefully according to your doctor’s instructions.
  
  
• Do Not Take Late in the Day: Taking Dyanavel XR too late in the day can interfere with sleep, so it’s best to take it in the morning.
  
  
• Avoid Crushing or Chewing: Since Dyanavel XR is extended-release, do not chew or crush the medication, as this will affect how the drug is released and may increase the risk of side effects.
  
  

Missed Dose: If you miss a dose, take it as soon as you remember, but never take two doses at once to make up for a missed dose.

Dyanavel XR contains amphetamine, which works by increasing the levels of certain neurotransmitters, including dopamine and norepinephrine, in the brain. These neurotransmitters play a key role in regulating mood, focus, and behavior.

Here’s how Dyanavel XR works:

• Stimulates the Central Nervous System (CNS): The drug affects the CNS by increasing the release of dopamine and norepinephrine, which help regulate attention, concentration, and impulse control.
  
  
• Improves Focus and Attention: By balancing the levels of these neurotransmitters, Dyanavel XR can help individuals with ADHD concentrate better and stay focused on tasks for longer periods.
  
  

Reduces Hyperactivity: Dyanavel XR helps calm hyperactive behavior, making it easier for individuals to sit still and engage in activities that require sustained attention.

While Dyanavel XR is effective for treating ADHD, it may cause side effects. Not everyone will experience side effects, but common and serious ones include:

• Common Side Effects:
  
  
  • Loss of appetite: This is a common side effect and may lead to weight loss, especially in children.
    
    
  • Dry mouth.
    
    
  • Insomnia or difficulty sleeping.
    
    
  • Nausea or stomach upset.
    
    
  • Headache.
    
    
  • Dizziness.
    
    
  • Increased heart rate.
    
    
• Serious Side Effects:
  
  
  • Heart Problems: Stimulants like Dyanavel XR can increase the risk of heart attack, stroke, or sudden death, especially in individuals with heart problems.
    
    
  • Mental Health Issues: Some individuals may experience new or worsening mental health issues, such as anxiety, paranoia, or aggression.
    
    
  • Severe allergic reactions: Symptoms may include rash, itching, or swelling, particularly in the face or throat.
    
    
  • Growth suppression: Long-term use in children may affect growth, so it’s important for doctors to monitor growth and weight regularly.
    
    
  • Addiction or Misuse: Dyanavel XR is a stimulant medication, and there is a risk of abuse or dependency, particularly if used inappropriately.
    
    

If you experience any of these serious side effects, seek immediate medical attention.

Before starting Dyanavel XR, there are important precautions and warnings to consider:

• Heart Conditions: Inform your doctor if you have any heart-related issues, such as a history of heart disease, high blood pressure, or irregular heartbeat, as stimulants can increase the risk of heart-related problems.
  
  
• Mental Health Conditions: Dyanavel XR can sometimes worsen symptoms of anxiety, bipolar disorder, or psychosis. If you have a history of mental health disorders, talk to your doctor before starting the medication.
  
  
• Substance Abuse History: If you or your child has a history of drug abuse or addiction, your doctor will carefully evaluate whether Dyanavel XR is appropriate.
  
  
• Growth Monitoring in Children: Long-term use of stimulants can sometimes affect growth. Children on Dyanavel XR should be regularly monitored for any signs of growth suppression or weight loss.
  
  

Pregnancy and Breastfeeding: The safety of Dyanavel XR during pregnancy is not well-established, so it should only be used if the benefits outweigh the risks. It is also unknown whether the medication passes into breast milk, so consult with your doctor before using it while breastfeeding.

• Monoamine Oxidase Inhibitors (MAOIs): Using Dyanavel XR with MAOIs can cause a severe hypertensive crisis (dangerously high blood pressure), so this combination should be avoided.
  
  
• Blood Pressure Medications: Dyanavel XR can increase blood pressure, so caution should be used if taken with antihypertensive medications.
  
  
• Other Stimulants: Combining Dyanavel XR with other stimulant medications (like other ADHD medications) can increase the risk of serious side effects, including increased heart rate and blood pressure.
  
  

Antidepressants: Some antidepressants, especially tricyclic antidepressants (TCAs), can interact with Dyanavel XR and increase the risk of serotonin syndrome, a potentially life-threatening condition.

The typical dosage of Dyanavel XR depends on the individual’s needs and medical history:

• Starting Dose: For children aged 6 years and older, the starting dose is usually 2.5 mg once a day, taken in the morning. For adults, the dosage may vary depending on the condition being treated.
  
  
• Titration: The dose may be gradually increased by 2.5 mg increments until the optimal dose is found, based on symptom control and side effect tolerance.
  
  

Maximum Dose: The maximum recommended dose is generally 20 mg per day.

Dyanavel XR is a prescription-only medication. A healthcare provider will assess the individual’s health condition and symptoms before prescribing it. It is important to follow the doctor’s instructions regarding dosage and frequency to ensure the medication is used safely and effectively.

• What is Dyanavel XR?
  A central nervous system (CNS) stimulant prescription medicine containing amphetamine, used once-daily (extended-release) for ADHD in people 6 years and older. 

• How does Dyanavel XR work?
  It blocks the reuptake and increases release of norepinephrine and dopamine in the brain. 

• What forms does it come in?
  Extended-release oral suspension (liquid) and extended-release tablets (5 mg, 10 mg, 15 mg, 20 mg). 

• What dosing options are available?
  Start at 2.5 mg or 5 mg once daily in the morning; can increase by 2.5–10 mg every 4–7 days up to a maximum of 20 mg/day. 

• How should the liquid form be used?
  Shake well, use the supplied dispenser, take once daily in the morning with or without food. 

• How should tablets be administered?
  May be chewed or swallowed whole; the 5 mg tablet is scored and divisible to 2.5 mg pieces. 

• How long does it last?
  Starts working in about 1 hour and provides symptom control for up to 13 hours. 

• What technology enables its extended-release?
  Utilizes Tris Pharma’s LiquiXR® ion-exchange polymer technology—a mix of immediate- and extended-release particles. 

• Is there a difference between liquid and tablet?
  No difference in effect or dosing—they are interchangeable. 

• What age groups is it approved for?
  Approved for children and adults aged 6 years and older; safety in under-6 not established. 

• Is Dyanavel XR habit-forming?
  Yes—it’s a federally controlled substance (Schedule II) with high potential for abuse and dependence. 

• What class of drug is it?
  CNS stimulant—amphetamine class. 

• What safety monitoring is needed?
  Monitor for abuse, heart issues, blood pressure, psychiatric symptoms, growth in children, tics, and signs of circulation problems. 

• What are contraindications?
  Allergy to amphetamines, use of MAO inhibitors in the past 14 days, and known hypersensitivity. 

• What common side effects occur?
  Dry mouth, decreased appetite, weight loss, insomnia, stomach pain, mood changes, headache, dizziness. 

• What serious risks are associated?
  Sudden death in those with heart defects, psychiatric events (mania, psychosis), circulation problems (Raynaud’s), serotonin syndrome. 

• Can it be substituted milligram-for-milligram with other amphetamines?
  No—due to differing amphetamine salts and pharmacokinetic profiles. 

• How effective is it in children?
  In laboratory classroom studies (ages 6–12), significant improvement in ADHD symptoms at all measured timepoints up to 13 hours. 

• Is supply readily available?
  Yes—Tris Pharma ensures continued supply, including during Adderall shortages. 

• Are there support or savings programs?
  Yes—programs like “DYANAVEL Delivered” offer guaranteed availability, delivery, patient support, and copay savings (e.g., $25/month).